Proton radiation with chemo and immunotherapy for esophageal cancer
Part of Cancer, Digestive system clinical trials.
This trial tests a new combination of proton beam radiation, chemotherapy, and immunotherapy for locally advanced esophageal squamous cell carcinoma. It aims to see if this approach is safe and may help people whose cancer cannot be surgically removed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- Your daily activity level is good (ECOG 0 or 1).
- You have been diagnosed with squamous cell carcinoma of the esophagus, stage II, III, or IVA (by imaging).
- Your cancer cannot be removed by surgery, or you have chosen not to have surgery.
- You have not had any previous cancer treatment (like chemotherapy, radiation, or immunotherapy).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a treatment for locally advanced esophageal cancer. You'll receive chemoradiation (chemo plus radiation) followed by a maintenance drug (a PD-1 inhibitor) to help prevent the cancer from coming back.
This trial tests a combination of radiation, chemotherapy (cisplatin and paclitaxel), and an immunotherapy drug called camrelizumab for patients with advanced esophageal squamous cell carcinoma that cannot be surgically removed. The goal is to see if adding immunotherapy improves outcomes compared to standard treatment alone.
This trial tests a combination of low-dose radiation and immunotherapy for people with advanced esophageal cancer that cannot be surgically removed. The goal is to see if this approach is safe and effective after initial treatment.
This trial compares the current standard treatment (chemotherapy and radiation) with a newer approach that combines chemotherapy and immunotherapy before surgery for esophageal cancer. Participation may help determine if this new combination is more effective for you.
This trial studies whether proton therapy can better treat early-to-mid stage esophagus cancer while aiming to reduce side effects to nearby organs. Proton therapy uses a targeted type of radiation, and participants are also checked to be eligible for curative surgery.
This trial tests whether adding radiation therapy to a standard treatment (immunotherapy plus chemotherapy) can help people with advanced esophageal cancer that has spread to up to two organs. The goal is to see if the combination improves outcomes.
Hear when a new Esophageal Carcinoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.