Clinical trials
Post Endodontic Pain clinical trials
Below are recruiting post endodontic pain clinical trials, each written for real people, not researchers. We’re tracking 15 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07767084Recruiting
Sealer type and pain after root canal treatment
This study compares two types of dental sealers (materials used to fill the root canal) to see if one causes less pain after the procedure. It may help you know what to expect and allow you to choose a treatment that reduces discomfort.
MinyaAges 18–45 - NCT07400471RecruitingEarly Phase 1
Pain relief before root canal: a medicine combination
This trial tests whether a combination of pain medicines given before a root canal can lower pain afterward. It is for people who have moderate to severe tooth pain and are healthy enough for standard treatment.
Chittagong, ChattogramAges 18 years+ - NCT07275710Recruiting
Alprazolam for tooth pain after root canal
This trial tests if adding alprazolam (a mild anti-anxiety medicine) to standard painkillers can better manage pain after a root canal. It aims to find a more effective way to control post-procedure discomfort.
Rawalpindi, Punjab ProvinceAges 18–60 - NCT06977009Recruiting
Does tooth grinding relief help with post-dental pain?
This study tests whether reducing a tooth's contact with its opposite tooth before root canal treatment can lower pain after the procedure. It's for people with a dead nerve in a back molar that needs a crown.
Amman, Amman GovernorateAges 18–70 - NCT06980870RecruitingPhase 2
Pain medicine before root canal for less discomfort
This study tests whether taking ibuprofen or dexamethasone before a root canal can help reduce pain afterward. It's for people with a painful, inflamed tooth nerve who haven't already taken pain medicine for it.
RawalpindiAges 18–50 - NCT07036237Enrolling by invitation
Comparing pain relief rinses after root canal
This trial tests whether rinsing the tooth with either tramadol (a pain reliever) or dexamethasone (a steroid) after a root canal reduces pain better. It is for people with a single-rooted tooth that has a very painful, inflamed nerve.
Karachi, SindhAges 18–50 - NCT07759349RecruitingEarly Phase 1
Pain relief choices after root canal treatment
This study compares three different pain relievers to see which works best for pain after a single-visit root canal. It may help find better ways to manage post-procedure discomfort.
Karachi, SindhAges 18–60 - NCT06671743RecruitingPhase 3
Medication before root canal to reduce pain
This study tests whether taking a medication before a root canal can reduce pain afterward. It is for people who need a root canal on a lower back tooth that has a painful, inflamed nerve but no infection at the root tip.
AjmanAges 20–50 - NCT06562816RecruitingPhase 4
Comparing two pain relievers after root canal treatment
This study tests two different pain medicines (trypsin-chymotrypsin and naproxen sodium) to see which one works better for pain after a root canal. It may help you if you need a root canal and are generally healthy.
Karachi, SindhAges 18–45 - NCT07785973Recruiting
Comparing two root canal fillings for pain and healing
This study compares two types of root canal filling materials to see which one causes less pain after the procedure and helps the infection at the tooth root heal better. It focuses on upper front teeth with an active infection.
MinyaAges 20–40 - NCT07571837Recruiting
Nano-medication to reduce inflammation after root canal retreat
This study tests a special nano-sized (extremely tiny) medication placed inside a tooth after a previous root canal treatment failed. The goal is to reduce inflammation and swelling in the bone around the tooth's tip so it can heal better.
Cairo, Nasr CityAges 20–40 - NCT07800403Recruiting
Nanoparticle disinfection for root canal infection in diabetes
This trial tests a new disinfection approach during root canal treatment for people with type 2 diabetes who have an infected front tooth. It aims to improve the effectiveness of the cleaning step, which may help treat the infection better.
MinyaAges 18–40 - NCT06836882Recruiting
Testing cavity disinfectants for deep tooth decay pain
This study tests two cavity disinfectants to see which one better reduces pain and improves healing after removing deep decay from back teeth. It is for adults with deep cavities in their lower molars that are still alive (not needing a root canal).
HaryānaAges 18 years+ - NCT07075055Recruiting
New bioceramic medication for infected front teeth
This trial tests a new bioceramic medication placed inside the root canal of infected front teeth to see if it improves healing. It is for adults with mature front teeth and an infection around the root tip, who are otherwise healthy.
MinyaAges 18–40 - NCT07836920Recruiting
Comparing two tooth-restoration approaches after root canal treatment
This study compares two ways to restore teeth that have had root canals, focusing on back teeth. It aims to see which approach is more conservative and effective, which may help preserve more of your natural tooth and improve long-term outcomes.
Cairo, ManialAges 20–50
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Common questions
- Are there clinical trials for post endodontic pain?
- Yes. Clin2 currently lists 15 recruiting post endodontic pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post endodontic pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post endodontic pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.