Immunotherapy plus chemo before stomach/esophagus cancer surgery
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests adding an immunotherapy drug (tislelizumab) to standard chemotherapy (FLOT) before surgery for people with stomach or esophagus cancer that can be removed but hasn't spread. The goal is to see if this combination is safe and works better than chemotherapy alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of stomach, esophagus, or junction cancer that can be surgically removed and hasn't spread to distant organs.
- Your cancer has not been treated with chemotherapy, radiation, or immunotherapy before.
- You are generally active (able to do light work) and have good organ function (kidney, liver, blood counts).
- You do not have active autoimmune disease, lung inflammation, or a serious heart condition.
- You are willing to use effective birth control if needed during and shortly after treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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