Tranexamic acid to reduce bleeding during cesarean section
Treatments studied
Part of Blood & lymphatic, Women’s health & pregnancy clinical trials.
This study tests whether giving tranexamic acid, a medicine that helps blood clot, before a cesarean section can reduce blood loss during and after the surgery. It may help women who are at higher risk of bleeding during delivery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are pregnant and between 37 and 42 weeks of pregnancy.
- You are scheduled for a cesarean section (C-section) for reasons such as placenta previa, severe preeclampsia, uterine fibroids, large baby, too much amniotic fluid, having had 5 or more previous deliveries, or prolonged labor.
- You have no known allergy to tranexamic acid.
- You have no history of blood clots (deep vein thrombosis, pulmonary embolism), heart attack, stroke, or seizures.
- You do not have heart, kidney, or liver disease, and you have not taken blood-thinning or antiplatelet medicines within the last week.
- You do not have placenta accreta, placental abruption, eclampsia, HELLP syndrome, or a failed vacuum or forceps delivery, and you are not carrying more than one baby.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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