Using Nitroglycerin to Prevent Pancreatitis After ERCP
Treatments studied
Part of Digestive system clinical trials.
This study tests if spraying nitroglycerin into the bile duct during an ERCP procedure can lower the risk of pancreatitis (inflammation of the pancreas) after the procedure. It is for people who need to have gallstones removed from their main bile duct.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You need an ERCP procedure to remove gallstones from your main bile duct.
- You do not have pancreatic cancer.
- You are not in shock (very low blood pressure or on medication to support blood pressure).
- You are not allergic to nitroglycerin (NTG).
- You do not have angle-closure glaucoma, severe anemia, or take PDE5 inhibitors (like sildenafil/Viagra).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether rinsing the pancreas with cold water during ERCP can reduce the risk of pancreatitis, a common complication. The treatment is added to the standard medicine (indomethacin) to see if it offers extra protection.
This trial tests whether giving extra IV fluids before, during, and after an ERCP procedure can help prevent a common complication called post-ERCP pancreatitis (inflammation of the pancreas). If you are scheduled for an ERCP, you may be eligible to participate.
This study tests whether adding ice water irrigation to standard rectal indomethacin reduces the risk of inflammation of the pancreas after ERCP, a procedure that examines the bile and pancreatic ducts. It may help prevent a painful complication.
This study tests whether doing an ERCP (a procedure to clear gallstones from the bile duct) right away helps people with mild gallstone-related pancreatitis who choose not to have their gallbladder removed. It looks at whether this approach helps with recovery and symptoms.
This study tests whether a rectal dose of indomethacin (an anti-inflammatory drug) can help prevent complications after an ERCP. It is for people who have already had a sphincterotomy and are having another ERCP to treat bile duct issues.
This trial tests if giving fluids before an ERCP procedure can lower the risk of developing pancreatitis (inflammation of the pancreas). It may help people who have not had this procedure before.
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