Indomethacin for bile duct procedure patients
Treatments studied
Part of Digestive system clinical trials.
This study tests whether a rectal suppository of indomethacin (a type of anti-inflammatory) can help prevent complications during a bile duct procedure called ERCP. It's for people who have already had a prior bile duct cut.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are scheduled for a routine bile duct procedure (ERCP) and have had a prior bile duct cut (sphincterotomy).
- You can receive medication as a rectal suppository.
- You are not allergic to indomethacin, aspirin, or other NSAIDs like ibuprofen.
- You do not have active stomach bleeding or a history of NSAID-related ulcers.
- You are not pregnant, breastfeeding, or planning to become pregnant during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two common NSAID medications (indomethacin and diclofenac) given before an ERCP procedure to see if one is better at preventing pancreatitis, a common complication. If you are having an ERCP and meet the health criteria, you may be able to join.
This study compares indomethacin (an anti-inflammatory medicine) against using a temporary pancreatic stent to prevent pancreatitis after an ERCP procedure. It may help you lower the chance of painful inflammation of the pancreas after ERCP.
This study compares a low dose of indomethacin (a pain reliever) with the standard dose to see if it works just as well for preventing pancreatitis (inflammation of the pancreas) after an ERCP procedure. It may reduce side effects while still protecting your pancreas.
This trial is testing whether higher doses of a common anti-inflammatory drug (indomethacin) given as a suppository can better prevent pancreatitis after an ERCP procedure in people who are at high risk for this complication.
This trial tests whether giving extra IV fluids before, during, and after an ERCP procedure can help prevent a common complication called post-ERCP pancreatitis (inflammation of the pancreas). If you are scheduled for an ERCP, you may be eligible to participate.
This Phase 3 study tests whether putting an anti-inflammatory medicine into the rectum (indomethacin) plus taking an immune-suppressing pill (tacrolimus) works better than using the two medicines in a different combination to prevent pancreatitis after an ERCP procedure. If you qualify, you may be assigned to one of the treatment options to lower your risk of post-ERCP pancreas inflammation.
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