Role of bacteria in lower back disc disease
Part of Bones, joints & muscles, Pain clinical trials.
This trial looks at whether a specific bacteria, Cutibacterium acnes, is linked to disc problems in the lower back. If you're having surgery for a herniated disc, your tissue sample may help researchers understand the cause.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old
- You have an MRI in the past month showing a disc problem like a bulge or herniation
- You have symptoms matching the MRI, such as leg pain when lifting your leg, numbness, weakness, or changes in reflexes
- You haven't taken antibiotics or steroids in the month before surgery
- You don't have a current infection or a condition that weakens your immune system
- You don't have inflammatory arthritis or other rheumatologic diseases
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at MRI findings in people with lumbar disc disease to better connect imaging with symptoms. If you have low back pain or leg pain from a disc problem, this study may help improve understanding and future care.
This study collects health information after lower-back disc surgery to track outcomes over time. It may help improve how the surgery and devices are monitored in real-world patients.
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
This study tests if an injection can help people with a herniated disc in the lower back who have not gotten better with other treatments and are already planning surgery. It aims to see if the injection can reduce symptoms and possibly avoid or improve surgery outcomes.
This study tests whether a specific massage technique can help rebuild the muscles that stabilize your lower back, which may reduce pain and improve movement for people with a lumbar disc herniation. The goal is to correct the 'muscle-bone imbalance' that often causes back pain.
This study tests a new imaging tool called Nociscan to see if it helps doctors decide who will benefit from lumbar spine surgery for low back pain. It may help predict surgical outcomes and guide treatment.
Hear when a new Lumbar Disc Herniation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.