Clin2
NCT07089186Possibly a fitRecruiting

Study of meropenem and pralurbactam for certain antibiotic-resistant infections

Hospital-acquired Bacterial Pneumonia (HABP)Ventilator-associated Bacterial Pneumonia (VABP)Complicated Intra-abdominal Infection (cIAI)Complicated Urinary Tract Infection (cUTI)Bloodstream Infection (BSI)

Treatments studied

Part of Infections clinical trials.

This trial tests a combination of two antibiotics (meropenem and pralurbactam) for treating serious infections caused by bacteria that are resistant to many other antibiotics. It may be an option for hospitalized patients with pneumonia, urinary tract infections, abdominal infections, or bloodstream infections.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
80 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You are between 18 and 80 years old and are currently in the hospital.
  • You have a confirmed infection caused by carbapenem-resistant Enterobacteriaceae (a type of bacteria that doesn't respond to many common antibiotics).
  • Your infection is one of these types: pneumonia (lung infection), complicated urinary tract infection, complicated abdominal infection, or a bloodstream infection.
  • You have not received more than 24 hours of appropriate antibiotics for this infection, or your symptoms have not improved after at least 2 days of treatment.
  • You are expected to live for at least another 28 days.
  • You are not currently taking more than 3 systemic antibiotics and do not need treatment for longer than 21 days.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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