Clin2
NCT07096674Likely a fitRecruiting

Long-term study of ORX750 for narcolepsy and idiopathic hypersomnia

Narcolepsy Type 1Narcolepsy Type 2Idiopathic Hypersomnia

Part of Brain & nervous system, Mental health clinical trials.

This trial is for people who have already completed the main CRYSTAL-1 study of ORX750. It tests the long-term safety and effects of the drug, so you can continue treatment if it was helping you.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
90 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You must have been diagnosed with narcolepsy type 1, narcolepsy type 2, or idiopathic hypersomnia.
  • You must have finished the full treatment period in the earlier CRYSTAL-1 study of ORX750.
  • You must be willing and able to follow the study rules and procedures.
  • You cannot have developed a new medical condition that would make it unsafe to stay in the study.
  • You cannot take other medications for narcolepsy or idiopathic hypersomnia while in this study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06752668Recruiting· Phase 2
Testing ORX750 for narcolepsy and idiopathic hypersomnia

This trial tests an experimental drug called ORX750 for people with narcolepsy or idiopathic hypersomnia. You would need to stop your current sleepiness medicines to see if ORX750 helps reduce daytime sleepiness.

Auburn, Alabama
NCT06767683Recruiting· Phase 2/Phase 3
Long-term study of ALKS 2680 for narcolepsy and idiopathic hypersomnia

This study is for people with narcolepsy or idiopathic hypersomnia who have already taken part in an earlier ALKS 2680 study. It aims to see how well the medication works and how safe it is when taken for a longer time.

Cullman, Alabama
NCT07502443Recruiting· Phase 3
Study of ALKS 2680 for narcolepsy type 2

This study tests an investigational drug called ALKS 2680 for people with narcolepsy type 2, a condition that causes excessive daytime sleepiness without sudden muscle weakness. The goal is to see if the drug is safe and helps reduce daytime sleepiness.

Cullman, Alabama
NCT06843590Recruiting· Phase 2
Study of ALKS 2680 for Idiopathic Hypersomnia

This trial tests a new medicine called ALKS 2680 for people with Idiopathic Hypersomnia (a condition that causes extreme sleepiness without a clear cause). The goal is to see if it is safe and effective at helping you stay awake during the day.

Cullman, Alabama
NCT07455383Recruiting· Phase 3
Testing ALKS 2680 for adults with narcolepsy type 1

This study tests a new medication, ALKS 2680, to see if it helps reduce daytime sleepiness and other symptoms in adults with narcolepsy type 1. It may offer a new treatment option for people with this condition.

Cullman, Alabama
NCT05816382Recruiting· Phase 2/Phase 3
Testing TAK-861 for narcolepsy type 1 sleepiness

This Phase 2/3 study tests TAK-861 in people with narcolepsy type 1 (NT1) who already completed an earlier TAK-861 trial. The goal is to see if the medicine remains safe and effective for ongoing central (brain-related) sleepiness problems.

Birmingham, Alabama

Hear when a new Narcolepsy Type 1 trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.