Pain relief and safety of two medications for eye surgery
Treatments studied
Part of Eyes & vision clinical trials.
This study compares two pain medicines, oliceridine and oxycodone, given during eye surgery (vitrectomy) to see which works better and is safer. It aims to improve comfort during the procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You are having vitrectomy (eye surgery) with local anesthesia and sedation.
- Your pain before surgery is mild (3 or less on a 0-10 scale).
- You have no severe heart, lung, liver, or kidney problems.
- You are not allergic to opioids and have no history of opioid abuse.
- You have not taken pain or sedative medications within 24 hours before surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a combination of two pain medicines during strabismus (eye muscle) surgery. It aims to see if these medicines help reduce pain and improve recovery after surgery.
This study compares different numbing medicines (additives) mixed with lidocaine to see which works best for pain relief during eye surgery. All patients will receive a numbing injection around the eye (peribulbar block) to keep you comfortable during the procedure.
This study compares two medicines (fentanyl and ketorolac) added to the numbing injection used during eye surgery. The goal is to see which one works better to reduce pain and make the surgery more comfortable.
This trial tests a new painkiller called Oliceridine for patients who have had abdominal surgery. It aims to see how well it controls pain and if it is safe, which could help improve recovery after surgery.
This study tests a new pain medicine called oliceridine after laparoscopic upper abdominal surgery. It aims to improve pain control and recovery compared to standard opioids.
This trial compares two intravenous painkillers given after heart surgery to see which one controls pain better and how they affect heart function. If you are having heart surgery, the study may help find a safer, more effective way to manage your pain.
Hear when a new Vitrectomy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.