Treatment
Oxycodone clinical trials
We’re tracking 34 recruiting studies that include Oxycodone, each written for real people, not researchers, below.
Recruiting studies
- NCT05795478Recruiting
Oxycodone plus pregabalin for long-term pain after spinal surgery
This trial studies whether taking oxycodone together with pregabalin (both pain medicines) can reduce chronic pain that can linger after spinal surgery. If you qualify, you may be asked to rate your pain and complete questionnaires during recovery.
BeijingAges 18 years+ - NCT07153003Enrolling by invitationPhase 4
Tramadol and oxycodone vs oxycodone alone for joint pain
This trial tests if taking two pain relievers (tramadol and oxycodone) together works better than oxycodone alone to control pain after knee or hip replacement surgery. It aims to find a more effective way to manage pain with fewer side effects.
Rochester, MinnesotaAges 18 years+ - NCT04218409RecruitingEarly Phase 1
Tests a spray to reduce opioid use and pain
This early trial studies whether Syntocinon can lower pain and help reduce how much opioids people use. It checks safety and the best dose by giving participants the study drug under close medical monitoring.
Gainesville, FloridaAges 21–45 - NCT05761860RecruitingEarly Phase 1
Oxytocin to lower opioid misuse risk and pain in older adults
This early-phase study tests whether oxytocin (a hormone-like medication) can reduce how “appealing” opioids feel and also reduce pain. It’s aimed at older adults who have used opioids before but are not currently dealing with chronic pain most days.
Gainesville, FloridaAges 45–85 - NCT05846451RecruitingEarly Phase 1
Study of how kratom and oxycodone interact in healthy adults
This early study tests how kratom can change the body’s handling of oxycodone (a prescription opioid) and how safe and measurable the effects are. It may help researchers understand drug interactions, especially for people who have used kratom and opioids before.
Spokane, WashingtonAges 21–45 - NCT07709598RecruitingPhase 2/Phase 3
HL-1186 for pain after abdominal surgery
This study tests a new painkiller called HL-1186 for people having abdominal surgery. If you qualify and enroll, you will receive the drug after surgery to see if it safely helps reduce your pain better than a placebo (a pill with no medicine).
Chengdu, SichuanAges 18–75 - NCT06186141RecruitingPhase 4
Comparing morphine and oxycodone for kids' pain after surgery
This study compares two common pain medicines—morphine and oxycodone—given through a PCA pump after surgery in children. The goal is to see which one causes less nausea and vomiting, so your child can recover more comfortably.
Melbourne, VictoriaAges 6–18 - NCT03823534RecruitingPhase 3
Study pain control after preventive femur bone surgery
This Phase 3 study tests a pain medicine plan used after preventive surgery to place a metal rod inside the thigh bone (femur) before a fracture happens. The goal is to find an approach that controls post-surgery pain while being safe for the right patients.
St Louis, MissouriAges 18 years+ - NCT07699601RecruitingPhase 2/Phase 3
Testing a pain tablet after orthopedic surgery
This trial tests an investigational tablet called HL-1186 for controlling pain after orthopedic surgery. It explores whether the drug can safely reduce moderate to severe pain when given after the procedure.
Changsha, HunanAges 18–75 - NCT06517069Recruiting
Acupuncture plus medication for pain after gynecologic surgery
This study tests whether adding a type of acupuncture (TEAS) to pain medication can better control pain after laparoscopic gynecologic surgery. It aims to improve recovery and comfort.
Yangzhou, JiangsuAges 18–65 - NCT06532708Recruiting
Pain Medicine Use After Laparoscopic Hysterectomy
This study looks at how doctors prescribe pain medicine after laparoscopic hysterectomy (a type of keyhole surgery to remove the uterus). It aims to find better ways to manage pain after surgery.
Memphis, TennesseeAges 18–80 - NCT07001709RecruitingPhase 4
How abiraterone affects oxycodone in prostate cancer
This study looks at how a common prostate cancer drug (abiraterone) affects how the body processes a painkiller (oxycodone). Men with prostate cancer who take abiraterone will be compared with those who do not, to see if the painkiller works differently.
Deventer, OverijsselAges 18 years+ - NCT07651722Recruiting
Pain control and gut recovery after abdominal surgery
This trial tests a combination of two pain-management approaches—a long-acting numbing medicine injected near nerves and a self-administered opioid—to see if they help your gut function better and control pain after bowel or colon surgery.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT07219888Enrolling by invitationPhase 4
Comparing suzetrigine and oxycodone for knee replacement pain
This study compares a new pain medicine called suzetrigine with a commonly used opioid, oxycodone, for pain after a knee replacement. The goal is to see which works better and has fewer side effects.
Louisville, KentuckyAges 21–89 - NCT03685188Enrolling by invitationPhase 4
Oxycodone and sufentanil pain medicine for hip surgery
This trial tests whether using oxycodone and sufentanil helps control pain during one-sided hip surgery. It’s meant to see how well these pain medicines work and whether they are safe for patients in this setting.
Chengdu, SichuanAges 18 years+ - NCT07773155RecruitingPhase 4
Pain control after hand or wrist surgery: nerve block with or without ketorolac
This study tests two different pain relief methods after hand or wrist surgery: a nerve block alone versus a nerve block plus an anti-inflammatory medication called ketorolac. The goal is to see which approach provides better pain control with fewer side effects.
Chicago, IllinoisAges 18 years+ - NCT06500793RecruitingPhase 1
Study of oxycodone with nafamostat in healthy adults
This trial tests how a new combination of oxycodone and nafamostat works in the body. It is for healthy volunteers aged 18 to 55 to help understand the drug's safety and how it is processed.
Miami, FloridaAges 18–55 - NCT03511118Recruiting
Drug safety study for breastfeeding mothers and babies
This study measures how common medicines move through a breastfeeding parent’s milk and checks safety in both the parent and breastfed baby. It may help doctors use these medicines more safely while you continue breastfeeding.
La Jolla, CaliforniaAges Any age - NCT07750639Enrolling by invitationPhase 4
Reducing painkiller use after hand surgery
This study tests a new approach to prescribing fewer opioid pain pills after hand, wrist, or elbow surgery. It aims to help reduce the risk of opioid misuse while still controlling pain after surgery.
Orlando, FloridaAges 18 years+ - NCT06878014RecruitingPhase 4
Morphine for pain relief after hip replacement surgery
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Sosnowiec, Silesian VoivodeshipAges 18–75 - NCT06505187RecruitingPhase 2
Celecoxib for Pain After Parotid Gland Surgery
This trial is testing whether the pain reliever celecoxib (Celebrex) can help control pain after a specific type of salivary gland surgery called superficial parotidectomy. If you're having this surgery, you may be able to join and take celecoxib for pain rather than other common pain medicines.
Madison, WisconsinAges 18 years+ - NCT06690307RecruitingPhase 4
Comparing two pain medicines after laparoscopic hysterectomy
This study compares two pain medicines, oxycodone and sufentanil, given through a pump you control after a laparoscopic hysterectomy. The goal is to see which one provides better pain relief with fewer side effects.
Nantong, JiangsuAges 18–65 - NCT03427736Recruiting
Studying pain and numbing medicines in children
This trial looks at how well different numbing and pain-relief medicines work in children during routine care. It may help doctors choose safer, better pain control for kids who need these medicines.
Stanford, CaliforniaAges birth–17 years - NCT03759028RecruitingPhase 4
Study of pain relief after elbow fracture surgery
This trial looks at how well different pain medicines work after surgery for a specific type of broken elbow bone. It may help find a safer, more comfortable pain-control plan while the fracture heals.
Los Angeles, CaliforniaAges 4–12
What Oxycodone is being studied for
Conditions with recruiting Oxycodone studies.
Common questions
- Are there clinical trials studying Oxycodone?
- Yes. Clin2 currently lists 34 recruiting studies that include Oxycodone, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Oxycodone trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Oxycodone an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Oxycodone or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.