Study of MKP10241 for weight loss and diabetes control
Part of Hormones & metabolism clinical trials.
This study tests an investigational drug called MKP10241 in healthy people, people with obesity, and people with type 2 diabetes. It aims to see how the drug affects blood sugar, weight, and overall safety. It may be an option if you have obesity or type 2 diabetes managed by diet and/or metformin.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- You are either a healthy volunteer (BMI 18–30) or have obesity (BMI 32 or higher) and possibly type 2 diabetes.
- If you have diabetes, your blood sugar (fasting) must be between 125 and 260 mg/dL, and your diabetes must be managed by diet/exercise or a stable dose of metformin.
- You must not smoke more than 5 cigarettes a day and agree not to drink alcohol for 48 hours before dosing until the end of the study.
- You must be willing to stay at the study clinic for periods of time and follow all study rules.
- You cannot have a history of seizures, major surgery within the past 2 months, or certain liver, kidney, or heart problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests an experimental medication called ARO-INHBE in adults with obesity, including those who also have type 2 diabetes. The goal is to see if it helps with weight loss and is safe.
This study tests whether a new medicine called NNC0487-0111 helps people with type 2 diabetes and excess weight lose weight. You'll take the medicine along with your current diabetes care to see if it works better than standard treatment.
This early-stage study tests a new investigational medication in three groups: healthy adults with normal weight, adults who are overweight or obese, and men with type 1 diabetes who are also overweight. The research aims to understand how safe the medication is and how the body processes it.
This study tests an investigational medicine for weight loss in people with excess weight. It aims to see how effective the medicine is and may help you lose weight and improve health.
This study tests a new medicine to see how well it helps people with excess body weight lose weight. It may be an option if you have tried to lose weight through dieting before but haven't had lasting success.
This early-stage study tests a new experimental medicine (NNC0113-5840) to see how it works in people who are overweight or have obesity. Researchers want to understand how the body processes this medicine and whether it's safe before testing it more widely.
Hear when a new Obesity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.