Safety study of NNC0497-0040 in healthy and overweight adults
Part of Hormones & metabolism, Immune system & allergy clinical trials.
This early-stage study tests a new investigational medication in three groups: healthy adults with normal weight, adults who are overweight or obese, and men with type 1 diabetes who are also overweight. The research aims to understand how safe the medication is and how the body processes it.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18–55 years old
- For healthy group: normal body weight (BMI 18.5–29.9); for other groups: overweight or obese (BMI 27–39.9)
- Blood sugar control test (HbA1c) below 6.5% (or below 7.2–9.5% if you have type 1 diabetes)
- No significant heart, kidney, liver, or other chronic health conditions (except diabetes-related conditions for the diabetes group)
- Willing to stop most prescription and non-prescription medications 2 weeks before the study starts
- Female participants must be unable to become pregnant, or male
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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