Clinical trials
Puberty clinical trials
Below are recruiting puberty clinical trials, each written for real people, not researchers. We’re tracking 31 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04884620Recruiting
Copenhagen puberty study for healthy Caucasian youth
This study looks at how puberty changes happen in healthy children and teens. By tracking normal development, researchers hope to better understand puberty timing and patterns.
CopenhagenAges 5–19 - NCT07859787Recruiting
Blood test for early or late puberty
This study checks if a blood marker called INSL3 can help doctors tell when puberty is starting early or late. It may help diagnose conditions like central precocious puberty or delayed puberty more accurately.
BolognaAges birth–18 years - NCT04113070Recruiting
Study of childhood weight and early puberty development
This study follows children to see how body weight changes relate to when puberty starts and how it progresses. It may help doctors better understand healthy growth patterns during childhood.
Shanghai, Shanghai MunicipalityAges 6–12 - NCT07864116Recruiting
Early puberty diagnosis test study
This study looks at a simpler blood test to diagnose early puberty in children. It checks if a single blood test can replace the longer, more complex stimulation test.
StrasbourgAges 4–11 - NCT07710430RecruitingPhase 4
Leuprorelin for children with central precocious puberty
This study tests a monthly injection of leuprorelin to see if it can slow or stop early puberty in children with central precocious puberty. It may help children who start puberty too early grow at a more typical pace.
SeoulAges Up to 10 years - NCT06690866Recruiting
Emotions and genetics during puberty in girls
This study looks at how emotions and genetics change during puberty in healthy girls. It involves questionnaires, interviews, and possibly an MRI scan to understand these changes.
Tübingen, Baden-WurttembergAges 8–17 - NCT06820931RecruitingPhase 4
Chinese medicine for girls with early puberty
This trial tests whether a Chinese herbal formula (nourishing yin, reducing fire) can help slow down rapid puberty in girls who started showing signs between 8 and 9 years old, before standard treatments are typically used. It aims to see if this option is safe and effective.
Shanghai, Shanghai MunicipalityAges 8–9 - NCT05008276Recruiting
Study of puberty, diabetes, and kidney stress in teens
This trial studies how puberty and blood sugar changes affect the kidneys in people with type 1 diabetes. It may help researchers understand early kidney risk and identify who needs closer monitoring.
Aurora, ColoradoAges 8–14 - NCT06777823Recruiting
Social media and mental health study for girls aged 10-11
This study looks at how social media affects the mental health of girls going through puberty. It tests whether sensitivity to rejection and puberty stage make some girls more vulnerable to social media experiences.
St Louis, MissouriAges 10 years+ - NCT06720844Recruiting
Precocious puberty and related brain conditions study
This study looks at children with central precocious puberty (early puberty that starts in the brain) to see how often it's linked with other developmental issues. It compares how these children develop and respond to treatment.
Bologna, BolgonaAges Up to 18 years - NCT06510764RecruitingPhase 3
Chinese medicine and acupuncture for early puberty in girls
This trial tests if Chinese traditional medicine plus intradermal acupuncture can help treat early puberty (precocious puberty) in girls. It aims to slow down puberty that started too soon, avoiding the need for stronger medications.
Shanghai, Shanghai MunicipalityAges 4–9 - NCT06280807Recruiting
How the environment affects reproductive health and hormones
This study looks at how the environment affects the body's reproductive system and hormone levels. By joining, you'll help researchers understand these connections over time, which may lead to better care for people with similar conditions.
Research Triangle Park, North CarolinaAges 8–99 - NCT06263868Recruiting
First study tracking early puberty signs
This study observes children who show signs of puberty earlier than usual. It aims to better understand early and advanced puberty by tracking children's development.
Écully, Auvergne-Rhône-AlpesAges Up to 11 years - NCT01601171Recruiting
Genetic study of reproductive problems and cleft lip or palate
This study looks at genetic (inherited) causes of certain hormone and reproductive conditions, including Kallmann syndrome and cleft lip/palate. You might be asked for medical and family history and possibly a DNA sample, helping researchers find what drives these conditions.
Lausanne, Canton of VaudAges Any age - NCT03283852Recruiting
Genetic study for certain childhood hormone and development disorders
This study looks for new genetic causes of certain “development disorders” that involve hormone problems and how the body develops at puberty. It may help families understand the root cause, which can guide future care and testing.
ParisAges Any age - NCT07703488Recruiting
Dydrogesterone for abnormal uterine bleeding in teens
This trial tests if dydrogesterone, a hormone pill, can safely help teenagers with heavy or irregular periods. If you or your child have had unusual bleeding that isn't caused by pregnancy or other medical issues, this study may provide treatment options.
Guangzhou, GuangongAges 10–19 - NCT06294990RecruitingPhase 4
Testosterone treatment for boys with Klinefelter syndrome in puberty
This trial tests if starting testosterone treatment during puberty (ages 10-14) helps boys with Klinefelter syndrome. It aims to understand how the hormone affects development and well-being.
CopenhagenAges 10–14 - NCT07379801Recruiting
Ballet dancers with scoliosis: A study on bone health and exercise
This study looks at how scoliosis affects the bones and muscles of young female ballet dancers during puberty. It also tests whether a special exercise program can help. Eligible dancers will be followed for a year.
HaifaAges 11–16 - NCT07102797Recruiting
ActiveGirls: Activity, hormones, and diabetes risk in young girls
This study looks at how physical activity and hormone health affect diabetes risk in young girls. It is for girls ages 8 to 12 who are at risk for PCOS (a hormone condition) and insulin resistance, and who have not yet started their period.
Somerville, MassachusettsAges 8 years+ - NCT04482374Recruiting
Puberty blockers and heart/metabolic health in teens
This study looks at how puberty suppression (puberty blockers) may affect heart health and metabolism in children who are early in puberty. It may help researchers understand who benefits most and what changes happen during treatment.
Aurora, ColoradoAges 9–14 - NCT00929006RecruitingEarly Phase 1
Testing progesterone effects on hormone timing during sleep in teens
This early-phase study tests whether a progesterone medicine can change when “luteinizing hormone” (a puberty-related hormone) pulses during wake versus sleep. It focuses on pubertal girls with either normal or higher-than-expected testosterone levels to see how their hormone timing responds.
Charlottesville, VirginiaAges 10–17 - NCT03068910RecruitingEarly Phase 1
Study of hormone timing in teens with high androgens
This early study looks at how certain “male-type” hormones and brain signals (measured through hormone patterns during the day and night) work in adolescent girls with high androgen levels. It may help researchers better understand causes like PCOS and related hormone timing differences.
Charlottesville, VirginiaAges 10–17 - NCT04723862RecruitingEarly Phase 1
Spironolactone to test sleep hormone patterns in teen girls
This early-phase study tests whether spironolactone can “normalize” a key hormone timing pattern during sleep and wake cycles in mid-to-late pubertal girls who have high male-hormone levels. The goal is to learn how this medicine may affect hormone rhythms related to conditions like PCOS.
Charlottesville, VirginiaAges 10–17 - NCT06670053Recruiting
Testosterone and brain development in teens
This study looks at how starting testosterone therapy affects brain development in transgender and gender-diverse youth. It may help you and your doctor understand the changes to expect.
Aurora, ColoradoAges 12–20
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Puberty trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for puberty?
- Yes. Clin2 currently lists 31 recruiting puberty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a puberty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a puberty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.