Clinical trials
Puberty clinical trials
Below are recruiting puberty clinical trials, each written for real people, not researchers. We’re tracking 32 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04884620Recruiting
Copenhagen puberty study for healthy Caucasian youth
This study looks at how puberty changes happen in healthy children and teens. By tracking normal development, researchers hope to better understand puberty timing and patterns.
CopenhagenAges 5–19 - NCT06690866Recruiting
Emotions and genetics during puberty in girls
This study looks at how emotions and genetics change during puberty in healthy girls. It involves questionnaires, interviews, and possibly an MRI scan to understand these changes.
Tübingen, Baden-WurttembergAges 8–17 - NCT06777823Recruiting
Social media and mental health study for girls aged 10-11
This study looks at how social media affects the mental health of girls going through puberty. It tests whether sensitivity to rejection and puberty stage make some girls more vulnerable to social media experiences.
St Louis, MissouriAges 10 years+ - NCT06820931RecruitingPhase 4
Chinese medicine for girls with early puberty
This trial tests whether a Chinese herbal formula (nourishing yin, reducing fire) can help slow down rapid puberty in girls who started showing signs between 8 and 9 years old, before standard treatments are typically used. It aims to see if this option is safe and effective.
Shanghai, Shanghai MunicipalityAges 8–9 - NCT07710430RecruitingPhase 4
Leuprorelin for children with central precocious puberty
This study tests a monthly injection of leuprorelin to see if it can slow or stop early puberty in children with central precocious puberty. It may help children who start puberty too early grow at a more typical pace.
SeoulAges Up to 10 years - NCT04113070Recruiting
Study of childhood weight and early puberty development
This study follows children to see how body weight changes relate to when puberty starts and how it progresses. It may help doctors better understand healthy growth patterns during childhood.
Shanghai, Shanghai MunicipalityAges 6–12 - NCT05008276Recruiting
Study of puberty, diabetes, and kidney stress in teens
This trial studies how puberty and blood sugar changes affect the kidneys in people with type 1 diabetes. It may help researchers understand early kidney risk and identify who needs closer monitoring.
Aurora, ColoradoAges 8–14 - NCT06263868Recruiting
First study tracking early puberty signs
This study observes children who show signs of puberty earlier than usual. It aims to better understand early and advanced puberty by tracking children's development.
Écully, Auvergne-Rhône-AlpesAges Up to 11 years - NCT06280807Recruiting
Observation of Environment and Reproductive Health Effects
This study looks at how the environment and your body's natural hormones interact. It is for people with reproductive or hormone-related conditions such as low sex hormones (hypogonadism), infertility, early or late puberty, PCOS, or menopause. The researchers will observe participants over time to learn more about these conditions.
Research Triangle Park, North CarolinaAges 8–99 - NCT06510764RecruitingPhase 3
Chinese medicine and acupuncture for early puberty in girls
This trial tests if Chinese traditional medicine plus intradermal acupuncture can help treat early puberty (precocious puberty) in girls. It aims to slow down puberty that started too soon, avoiding the need for stronger medications.
Shanghai, Shanghai MunicipalityAges 4–9 - NCT06720844Recruiting
Precocious puberty and related brain conditions study
This study looks at children with central precocious puberty (early puberty that starts in the brain) to see how often it's linked with other developmental issues. It compares how these children develop and respond to treatment.
Bologna, BolgonaAges Up to 18 years - NCT00250159Recruiting
Natural history study for hormone-related excess androgen
This study follows people who may have too much “androgen” (a hormone) to learn what causes it and how it changes over time. You may be followed even if the exact cause is not yet known, and your results may help doctors better understand these conditions.
Washington D.C., District of ColumbiaAges 1 day–99 years - NCT04717349Recruiting
Study collects health information for kids’ and teens’ gynecology concerns
This is a research study that gathers information about pediatric and adolescent gynecology conditions. It may help researchers better understand these issues by learning about symptoms, care, and outcomes—without requiring a specific treatment.
Bethesda, MarylandAges 1 day–100 years - NCT01434368Recruiting
How the brain and hormones change during puberty
This study follows healthy 8‑year‑olds over time to understand how hormones and brain development change during puberty. Participants will have MRI scans, X‑rays, and other tests to track normal growth.
Bethesda, MarylandAges 7–35 - NCT05463120Enrolling by invitation
Follow-up study of early growth and puberty timing
This study follows families from an earlier infant feeding study to better understand what affects when puberty starts. It looks at growth and hormone-related health information to explain differences in pubertal development.
Bethesda, MarylandAges 8–100 - NCT04424576Recruiting
Study hormones and ovarian changes in teenage girls
This study looks at differences in ovarian structure and related hormone or metabolic patterns in adolescent girls soon after their first period. It may help researchers better understand early changes that can be linked to conditions like PCOS (polycystic ovary syndrome).
Kansas City, MissouriAges 9–17 - NCT07379801Recruiting
Ballet dancers with scoliosis: A study on bone health and exercise
This study looks at how scoliosis affects the bones and muscles of young female ballet dancers during puberty. It also tests whether a special exercise program can help. Eligible dancers will be followed for a year.
HaifaAges 11–16 - NCT06072677Recruiting
Mood and testosterone in young teens
This study looks at how mood changes during puberty in young people aged 11 to 14. It tests whether using a mindfulness app (Healthy Minds) can help teens who have been through stress or feel down.
Chapel Hill, North CarolinaAges 11–14 - NCT03068910RecruitingEarly Phase 1
Study of hormone timing in teens with high androgens
This early study looks at how certain “male-type” hormones and brain signals (measured through hormone patterns during the day and night) work in adolescent girls with high androgen levels. It may help researchers better understand causes like PCOS and related hormone timing differences.
Charlottesville, VirginiaAges 10–17 - NCT03283852Recruiting
Genetic study for certain childhood hormone and development disorders
This study looks for new genetic causes of certain “development disorders” that involve hormone problems and how the body develops at puberty. It may help families understand the root cause, which can guide future care and testing.
ParisAges Any age - NCT07703488Recruiting
Dydrogesterone for abnormal uterine bleeding in teens
This trial tests if dydrogesterone, a hormone pill, can safely help teenagers with heavy or irregular periods. If you or your child have had unusual bleeding that isn't caused by pregnancy or other medical issues, this study may provide treatment options.
Guangzhou, GuangongAges 10–19 - NCT04482374Recruiting
Puberty blockers and heart/metabolic health in teens
This study looks at how puberty suppression (puberty blockers) may affect heart health and metabolism in children who are early in puberty. It may help researchers understand who benefits most and what changes happen during treatment.
Aurora, ColoradoAges 9–14 - NCT04723862RecruitingEarly Phase 1
Spironolactone to test sleep hormone patterns in teen girls
This early-phase study tests whether spironolactone can “normalize” a key hormone timing pattern during sleep and wake cycles in mid-to-late pubertal girls who have high male-hormone levels. The goal is to learn how this medicine may affect hormone rhythms related to conditions like PCOS.
Charlottesville, VirginiaAges 10–17 - NCT05945576Recruiting
RaDiCo IDMet study for people with inherited ID
This study enrolls people of all ages who have a confirmed inherited condition called ID. It collects information to better understand the condition and support future care.
AngersAges Any age
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Puberty trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for puberty?
- Yes. Clin2 currently lists 32 recruiting puberty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a puberty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a puberty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.