Clin2
NCT07104643Possibly a fitNot yet recruiting

New drug with enzalutamide for advanced prostate cancer

mCRPC

Treatments studied

Part of Cancer, Kidney & urinary clinical trials.

This trial tests a new experimental drug (TYK-00540) combined with enzalutamide, an approved hormone therapy, for men with advanced prostate cancer that has spread and no longer responds to standard hormone therapy. The goal is to see if the combination can slow cancer growth better than current options.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
48 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Must be 18 years or older.
  • Have prostate cancer that has spread to other parts of the body and no longer responds to hormone therapy.
  • Must have already tried one new hormone treatment (like abiraterone or apalutamide) and it stopped working.
  • Cannot have been treated with enzalutamide before.
  • Must not have received certain other cancer treatments within the past 4 weeks (except standard hormone therapy).
  • Must be in generally good health with normal liver, kidney, and blood function.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07389187Not yet recruiting· Early Phase 1
Combination treatment for advanced prostate cancer

This trial tests a new combination of two drugs for men with advanced prostate cancer that has stopped responding to standard hormone therapy or chemotherapy. The goal is to see if this combination can help shrink tumors or slow the disease.

Shanghai, Shanghai Municipality
NCT07719361Recruiting· Phase 1
New drug for advanced, treatment-resistant prostate cancer

This study tests an experimental drug for men whose prostate cancer has spread and stopped responding to standard hormone therapies. It may be an option if your PSA is rising despite treatment with drugs like enzalutamide or abiraterone.

Los Angeles, California
NCT07103018Recruiting· Phase 1
Study of KTX-2001 for men with advanced prostate cancer

This trial tests a new drug called KTX-2001, possibly combined with another drug (darolutamide), for men whose prostate cancer has spread and stopped responding to standard hormone treatments. The goal is to see if it can help shrink tumors or slow the cancer's growth.

San Francisco, California
NCT07104617Not yet recruiting· Phase 1/Phase 2
Investigation of TY-302 combined with abiraterone for prostate cancer

This trial tests a new investigational medicine (TY-302) combined with abiraterone, a standard hormone-blocking drug, in men with metastatic castration-resistant prostate cancer. It aims to see if this combination can slow cancer growth after initial hormone therapy stops working.

Hangzhou, Zhejiang
NCT07311694Recruiting· Phase 3
Comparing a new treatment with standard drugs for advanced prostate cancer

This trial tests a new drug, HRS-4357, against standard treatments for men with a specific type of advanced prostate cancer that has spread and no longer responds to hormone therapy. It aims to see if the new drug works better.

Shanghai, Shanghai Municipality
NCT07683013Not yet recruiting· Phase 1
New drug with enzalutamide for advanced prostate cancer

This study tests a new drug called CP-PCA07 combined with enzalutamide for men whose prostate cancer has stopped responding to enzalutamide or abiraterone. The goal is to see if the combination is safe and can help control the cancer.

Seoul

Hear when a new mCRPC trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.