Clin2
NCT07389187Possibly a fitNot yet recruiting

Combination treatment for advanced prostate cancer

mCRPC

Treatments studied

Part of Cancer, Kidney & urinary clinical trials.

This trial tests a new combination of two drugs for men with advanced prostate cancer that has stopped responding to standard hormone therapy or chemotherapy. The goal is to see if this combination can help shrink tumors or slow the disease.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
10 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You are a man between 18 and 85 years old.
  • You have prostate cancer that has spread to your bones and is no longer controlled by hormone therapy or chemotherapy.
  • You have had at least one prior treatment like abiraterone, enzalutamide, or docetaxel.
  • You are willing to have a biopsy (tissue sample) taken before and during the study.
  • You have not been treated with immunotherapy (like PD-1/PD-L1 inhibitors) before.
  • You do not have cancer that has spread to organs like your liver or lungs.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07104643Not yet recruiting· Phase 1/Phase 2
New drug with enzalutamide for advanced prostate cancer

This trial tests a new experimental drug (TYK-00540) combined with enzalutamide, an approved hormone therapy, for men with advanced prostate cancer that has spread and no longer responds to standard hormone therapy. The goal is to see if the combination can slow cancer growth better than current options.

Hangzhou, Zhejiang
NCT07093866Recruiting· Phase 2
Targeted drug combo for advanced prostate cancer

This trial tests a combination of two drugs—disitamab vedotin (a targeted antibody-drug that attacks HER2-positive cancer cells) and abiraterone (a hormone therapy)—to see if they can slow or shrink prostate cancer that has spread and become resistant to standard treatments.

Nanjing, Jiangsu
NCT07244393Recruiting· Phase 1
Combination therapy for advanced prostate cancer

This trial tests a new combination therapy for advanced prostate cancer that has stopped responding to standard hormone treatments. It combines a radioactive targeted treatment (Lutetium-177 DGUL) with an immunotherapy drug (pembrolizumab) to see if it can shrink tumors and slow the cancer's growth.

Seoul
NCT07871435Recruiting· Phase 1/Phase 2
Investigational combo for advanced prostate cancer

This trial tests two investigational drugs together for men with a type of advanced prostate cancer that has stopped responding to standard hormone therapy. The goal is to see if the combination can shrink tumors or slow the cancer's growth.

New York, New York
NCT05613894Recruiting· Phase 1
Combination treatment for advanced prostate cancer

This study tests a combination of two drugs for men with advanced prostate cancer that has stopped responding to hormone therapy. The drugs are cabozantinib (a pill that may slow cancer growth) and a radioactive therapy that targets prostate cancer cells (177Lu-PSMA-617). The goal is to see if this combination is safe and effective.

Salt Lake City, Utah
NCT07219147Recruiting· Phase 1
Combination treatment for advanced prostate cancer

This trial tests a combination of two treatments for advanced prostate cancer that has stopped responding to hormone therapy. One treatment is a targeted radiation therapy (177Lu-PSMA-617) and the other is an immunotherapy (sipuleucel-T) that helps your immune system fight the cancer.

Duarte, California

Hear when a new mCRPC trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.