Clin2
NCT07109323Worth exploringRecruiting

Stem cell transplant plus CAR-T for aggressive myeloma

Ultra High Risk mm (uhr-mm), 18-70 Years Old, Suitable for ASCT. And Meet Any of the Following uhr-mm DefinitionsCytogenetics Ultra High RiskPrimary RefractoryEarly ProgressionPlasma Cell LeukemiaNon Paraosseous Extramedullary InfiltrationR2-ISS-IV /MPSS-IV

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This trial tests combining a stem cell transplant with a special immune cell therapy (BCMA CAR-T) to treat very aggressive multiple myeloma. The goal is to see if this powerful one-two punch can help people whose myeloma is hard to control.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
50 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You must have a very aggressive type of multiple myeloma, called ultra-high-risk myeloma.
  • You are between 18 and 70 years old.
  • Your doctor has said you are healthy enough for a stem cell transplant using your own cells.
  • You have not had a stem cell transplant before.
  • Your kidneys, liver, heart, and blood counts must be within safe limits for the trial.
  • You must not have other serious illnesses like uncontrolled infections, severe heart disease, or certain cancers in the last 3 years.

View the official record on ClinicalTrials.gov

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