Clin2
NCT07115238Possibly a fitRecruiting

PET imaging study for normal aging, MCI, and Alzheimer's

Alzheimer DiseaseNeurofibrillary Tangle

Part of Brain & nervous system, Mental health clinical trials.

This trial tests a new PET imaging agent (18F-XTR006) to see how well it shows brain changes related to Alzheimer's disease. It may help diagnose MCI (mild cognitive impairment) or Alzheimer's earlier by comparing images in healthy people and those with memory problems.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
354 people
Ages
50 years and older
Study type
Interventional

Who can take part

  • You are 50 years or older.
  • You can have both a PET scan and an MRI scan.
  • If you can become pregnant, you must use birth control during the study and for 6 months after.
  • You do not have other types of dementia, major mental illness, brain abnormalities, claustrophobia, or a history of alcohol or drug abuse.
  • You are not allergic to the study drug and are not breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04104659Enrolling by invitation
Tau PET scan study to map brain changes in Alzheimer’s

This study tests a PET scan “tracer” medicine called [18F]MK-6240 to see how tau protein changes show up in the brain. It may help researchers measure disease-related brain changes in people with normal thinking or mild dementia.

St Louis, Missouri
NCT06254469Recruiting· Phase 3
PET scan study for memory decline with head injury or Alzheimer's risk

This trial uses a special PET scan tracer to see if it can predict who will get worse over time. It is for people with mild memory or thinking problems that may be linked to past head injuries or early Alzheimer's disease.

Evanston, Illinois
NCT02414347Recruiting
Tau PET scan study for Alzheimer’s disease

This study uses a PET brain scan with a small injected tracer to look for “tau” protein changes linked to Alzheimer’s disease. It may help researchers better understand how tau appears in people who are cognitively normal or have mild dementia.

St Louis, Missouri
NCT06618872Recruiting
Comparing tau and amyloid PET scans for memory problems

This study compares two types of brain PET scans (tau and amyloid) to see which one better helps diagnose memory problems. You may be eligible if you have mild cognitive impairment or mild dementia and your doctor has already ordered an amyloid PET scan.

Geneva, Canton of Geneva
NCT05374278Recruiting· Phase 1/Phase 2
PET scan test for a dementia brain tracer

This early-phase study tests a new PET scan tracer that targets a brain chemical transport system involved in dementia. It aims to see if the tracer can safely and clearly show brain changes, which could help future dementia diagnosis or tracking.

San Francisco, California
NCT05582200Recruiting
PET brain scan to study inflammation cells in Alzheimer’s

This study uses a special PET brain scan to look at two types of brain immune cells in people with Alzheimer’s. It may help researchers better understand Alzheimer’s and how these cells change over time.

Houston, Texas

Hear when a new Alzheimer Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.