Comparing tau and amyloid PET scans for memory problems
Part of Brain & nervous system, Mental health clinical trials.
This study compares two types of brain PET scans (tau and amyloid) to see which one better helps diagnose memory problems. You may be eligible if you have mild cognitive impairment or mild dementia and your doctor has already ordered an amyloid PET scan.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 50 and 85 years old.
- You must have mild cognitive impairment or mild dementia (trouble with memory and daily tasks).
- You must have had an MRI brain scan in the last 6 months.
- Your doctor must have already ordered an amyloid PET scan for you.
- You cannot have other serious mental health conditions, severe white-matter changes in the brain, or signs of vascular dementia.
- You must not have metal implants or devices that are unsafe for MRI, and if you are a woman able to have children, you must not be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study uses brain scans to see how anti-amyloid treatments affect tau protein buildup in people with early Alzheimer's. If you have mild cognitive impairment or mild Alzheimer's, you may be eligible to help understand how these treatments work.
This study uses a PET brain scan with a small injected tracer to look for “tau” protein changes linked to Alzheimer’s disease. It may help researchers better understand how tau appears in people who are cognitively normal or have mild dementia.
This study tests a PET scan “tracer” medicine called [18F]MK-6240 to see how tau protein changes show up in the brain. It may help researchers measure disease-related brain changes in people with normal thinking or mild dementia.
This Phase 3 study uses a PET/CT scan to measure whether a brain protein called tau (and related disease patterns) builds up in different dementia conditions. The goal is to better match which disorders have which brain changes and how they progress.
This extension study looks for predictors—measurable clues—linked to memory changes in older adults who feel their memory is worsening. You may be asked to have an amyloid PET scan, which can help researchers understand what might be driving memory concerns.
This study uses a special brain scan to measure “tau” buildup in people with an inherited form of Alzheimer’s. It may help researchers better understand disease changes and evaluate whether the scan can track them over time.
Hear when a new Dementia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.