T-DXd with brain radiation for HER2+ breast cancer
Part of Cancer, Skin clinical trials.
This trial tests a new combination of a targeted drug (T-DXd) with brain radiation for women with breast cancer that has spread to the brain and is HER2-positive or HER2-low. The goal is to see if this approach is safe and works better than radiation alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 to 75 years with breast cancer that has spread to the brain.
- Your cancer must be HER2-positive or HER2-low (we can check with your doctor).
- You must be able to take care of most daily activities (ECOG score 0-2).
- You have not had radiation to the brain or treatment with T-DXd before.
- Your heart, blood, and other organs are working well enough (your doctor will test this).
- You do not have serious lung disease, uncontrolled infections, or other active cancers.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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