Intravenous alpha-1 antitrypsin for COPD hospital flare-ups
Part of Lungs & breathing clinical trials.
This trial tests whether giving an intravenous medication called alpha-1 antitrypsin can help people who are hospitalized with a sudden worsening of COPD (called an exacerbation). The medicine may help reduce lung inflammation and improve recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 40 years or older.
- You have a confirmed diagnosis of COPD.
- You are in the hospital right now because your COPD symptoms suddenly got much worse (an exacerbation).
- You have low oxygen levels in your blood when breathing room air, or you need more oxygen than your usual home prescription.
- A quick test of your sputum (phlegm) shows a high level of a certain enzyme called neutrophil elastase.
- You do not have other major lung conditions like pneumonia, asthma, or pulmonary fibrosis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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