Microneedling for chronic Peyronie's disease: a pilot study
Part of Kidney & urinary clinical trials.
This pilot study tests whether microneedling (tiny needles used on the skin) can safely and effectively reduce the curve caused by Peyronie's disease. If you have had a stable curve for at least 6 months and have not tried other treatments recently, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Peyronie's disease for at least 12 months, and your curve has been stable and pain-free for at least 6 months.
- Your penile curve is between 30 and 90 degrees (measured in one main direction).
- You are in a steady relationship with a female partner and willing to have vaginal intercourse (if you are not heterosexual, you can still join, but some questionnaires may not apply).
- You can get a firm enough erection for the doctor to measure the curve, with help from a penile injection if needed.
- You have not had other treatments for Peyronie's (like surgery, injections, shockwave, or pills) in the last 3 months, and you have never had collagenase (Xiaflex) treatment.
- You do not have a history of genital herpes (HSV), are not on blood thinners, and do not have other penis conditions or active sexually transmitted infections.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new type of laser treatment (fractional CO2 laser) to safely reduce penile curvature in men with chronic, stable Peyronie's disease. It may be an option if you have had the condition for at least a year with no recent changes or pain.
This trial tests whether injecting platelet-rich plasma (a concentration of your own blood cells) into the penile plaque can help reduce curvature from Peyronie's disease. It is for men whose curvature has been stable for at least 3 months and who have not had prior injections or surgery.
This study tests if injections of platelet-rich plasma from cord blood, combined with daily penis stretching, works better than stretching alone to treat Peyronie's disease (curved erections). It may help men with moderate to severe curvature who haven't had prior treatment.
This trial combines a low-intensity shockwave treatment with a commonly used injectable medication (collagenase) to see if the combination works better for men with Peyronie's disease who have a noticeable curve and a non-calcified plaque.
This trial compares two surgical techniques to correct severe penile curvature caused by Peyronie's disease. It tests which approach works better for men with advanced or complex cases.
This trial tests whether sound waves (extracorporeal shockwave therapy) can help men with stable Peyronie's disease reduce curvature and plaque. It's for those whose condition hasn't changed for at least 6 months and who haven't had other treatments.
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