Brain stimulation for temporal lobe epilepsy with bilateral hippocampal sclerosis
Part of Brain & nervous system clinical trials.
This trial tests a new type of brain stimulation for people with temporal lobe epilepsy whose seizures come from both sides of the brain and who haven't been helped by standard treatments. The goal is to reduce seizures by sending electrical signals to a specific area of the brain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 14 and 65 years old.
- Your seizures must not be controlled by anti-seizure medications, and you must have at least 3 disabling seizures every 3 months.
- You must not be a candidate for standard brain surgery (or you refused it), or that surgery or a heat-based procedure didn't work well enough.
- An MRI must show shrinkage (atrophy) in the hippocampus on both sides of your brain.
- You cannot have certain metal implants or devices (like a pacemaker or cochlear implant), but a stable vagus nerve stimulator is allowed.
- You must not have other serious conditions (like major depression, progressive brain disease, or severe kidney/liver problems) or be pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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