Focused brain surgery for hard-to-treat temporal lobe epilepsy
Part of Brain & nervous system clinical trials.
This trial tests a minimally invasive brain surgery that targets a small area deep in the brain to stop seizures in people whose epilepsy has not improved with medications. It may help reduce or eliminate seizures caused by scarring in the temporal lobe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 14 and 65 years old.
- You have epilepsy that has not improved with at least two anti-seizure medications.
- You still have at least 2 disabling seizures per month, with no gap longer than 30 days.
- Your MRI shows shrinkage or scarring in the hippocampus (a part of the brain involved in memory and seizures).
- Your EEG and PET scans show that your seizures start on one side of the brain, in the temporal lobe.
- You do not have other serious brain conditions, major psychiatric disorders, or a pacemaker or other implanted electrical device.
- You are not pregnant and do not plan to become pregnant within the next 2 years.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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