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NCT07129239Possibly a fitNot yet recruiting

High-dose aflibercept switch for wet age-related macular degeneration

Wet Age-related Macular Degeneration (wAMD)

Part of Eyes & vision clinical trials.

This study tests whether switching to a higher dose of aflibercept (Eylea) is safe and effective for people with wet age-related macular degeneration who are already receiving standard-dose aflibercept. The goal is to see if the higher dose can better control the disease and possibly extend the time between injections.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
180 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have neovascular (wet) age-related macular degeneration in at least one eye.
  • You have already had at least 3 initial (loading) and 2 follow-up (maintenance) injections of aflibercept (Eylea).
  • You do not have other eye conditions that affect the macula, such as polyps, dystrophy, or scarring.
  • You are not currently using a different anti-VEGF medication in your other eye, and you are not in another clinical trial.
  • You are not pregnant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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