Clin2
NCT07133750Likely a fitRecruiting

PM8002 plus chemo for untreated metastatic colorectal cancer

CRC (Colorectal Cancer)

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests a new combination therapy (PM8002 plus chemotherapy) for people with metastatic colorectal cancer who have not had prior treatment. It may be an option if your cancer is not MSI-H/dMMR and you are in good overall health.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
100 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 or older.
  • Your colorectal cancer must be metastatic (stage IV) and cannot be removed by surgery.
  • Your tumor must not be MSI-H or dMMR (a specific genetic type).
  • You cannot have had any prior chemotherapy or targeted therapy for metastatic disease.
  • You must be in reasonably good health (able to perform daily activities with little or no help).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07391566Not yet recruiting· Phase 1/Phase 2
Study drug with chemotherapy for advanced colorectal cancer

This trial tests a new drug combined with standard chemotherapy and another medication for people with advanced colorectal cancer that has a specific genetic change (RAS mutation). It aims to see if the combination can help control the cancer better.

Beijing
NCT07462143Recruiting· Phase 2/Phase 3
New drug plus chemo for advanced colorectal cancer

This trial tests a new drug (RC148) combined with standard chemotherapy as a first treatment for colorectal cancer that has spread or cannot be removed. The goal is to see if this combination works better than chemotherapy alone.

Beijing, Beijing Municipality
NCT05918445Recruiting· Phase 1/Phase 2
PM8002 for advanced solid tumors that have stopped responding

This Phase 1/2 study tests PM8002 in people with advanced solid cancers to see if it can work and is safe. It may help if your cancer has measurable disease and you have not fully recovered from side effects of prior treatment.

Baoji
NCT06841159Recruiting· Phase 2
Personalized radiation plus immunotherapy and chemo for metastatic colorectal cancer

This trial tests a new combination of ultra-precise radiation therapy, immunotherapy, chemotherapy, and targeted therapy for people with metastatic colorectal cancer that has a normal DNA mismatch repair system. The goal is to see if this personalized approach can better control the cancer and improve outcomes.

Shanghai
NCT06858969Not yet recruiting· Phase 2
Drug combination for advanced colorectal cancer

This study tests a new combination of drugs, including an immunotherapy and a targeted therapy, for colorectal cancer that has spread. The goal is to see if this combination can help shrink tumors or slow the cancer. It is designed for people who have not yet received treatment for metastatic disease.

NCT06764680Recruiting· Phase 2
Oral drugs and radiation for advanced colorectal cancer after standard therapy

This trial tests a combination of oral chemotherapy, targeted therapy, and immunotherapy, with or without radiation, for people with advanced colorectal cancer that hasn't responded to at least two prior treatments. The goal is to see if this approach can help shrink tumors or slow the disease.

Guangzhou, Guangdong

Hear when a new CRC (Colorectal Cancer) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.