Clin2
NCT07134335Worth exploringRecruiting

Study of UBT251 injection for chronic kidney disease

Obesity &Amp; OverweightChronic Kidney Disease

Treatments studied

Part of Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.

This study tests an investigational injection called UBT251 for people with chronic kidney disease who are overweight. It aims to see if it can reduce protein in the urine and help protect kidney function.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
180 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old with a BMI of 24 or higher.
  • Your kidney function is moderately reduced (eGFR between 45 and 90).
  • You have high levels of protein in your urine (UACR between 300 and 5000).
  • You have not used GLP-1 agonists or similar weight-loss drugs in the last 3 months.
  • You do not have certain kidney diseases (like lupus nephritis or polycystic kidney disease) or a history of pancreatitis.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07231679Recruiting· Phase 1/Phase 2
Study of IGT-303 for diabetic kidney disease

This study tests an investigational drug called IGT-303 in people with chronic kidney disease caused by type 2 diabetes. It aims to see if the drug is safe and helpful for slowing kidney damage.

Chula Vista, California
NCT07206290Not yet recruiting· Phase 2
Study of survodutide to reduce urine protein in kidney disease

This trial tests a new medication called survodutide to see if it can reduce protein in the urine and protect kidney function in people with chronic kidney disease. It may be an option for people who already take standard blood pressure and kidney-protecting pills.

NCT06717698Recruiting· Phase 2
Testing a new medicine for kidney damage in chronic kidney disease

This study tests different doses of an investigational medicine (NNC0519-0130) to see if it can reduce kidney damage in people with chronic kidney disease. It may be an option for you if you have kidney impairment and either have or don't have type 2 diabetes.

San Dimas, California
NCT07555054Not yet recruiting· Phase 2
Study of a new medicine for chronic kidney disease

This study tests a new medicine called HS-10390 to see if it can help people with chronic kidney disease. It might slow down the disease and protect your kidneys.

Guangzhou, Guangdong
NCT07648225Not yet recruiting· Phase 3
Weight loss injection study for overweight or obesity

This study tests an investigational injection called UBT251 to help people who are overweight or obese lose weight. It may also improve related health issues like high blood pressure or fatty liver. The trial lasts for a period and includes regular check-ins with the study team.

Beijing
NCT07559240Not yet recruiting· Phase 1
Kidney function study of an investigational injection

This study looks at how a new injection (HDM1005) is processed by the body in people with different levels of kidney function, including healthy volunteers. It aims to help understand dosing for people with kidney issues.

Beijing

Hear when a new Obesity &Amp; Overweight trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.