Study of NBM-BMX for advanced uveal melanoma that has spread
Part of Cancer, Eyes & vision clinical trials.
This trial tests a new oral drug, NBM-BMX, for people with metastatic uveal melanoma (melanoma of the eye that has spread). It aims to see if the drug is safe and effective. You may join if you have already tried some treatments, including tebentafusp if you are HLA-A*02:01 positive.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have been diagnosed with uveal melanoma that has spread to other parts of the body
- You are able to take care of yourself (ECOG performance status 0-2)
- You have not had a specific type of cancer drug called an HDAC inhibitor before
- Your heart, blood, liver, and kidney function are within certain limits based on blood tests
- You are willing to use two effective birth control methods if you or your partner could become pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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