Treatment
Esomeprazole clinical trials
We’re tracking 20 recruiting studies that include Esomeprazole, each written for real people, not researchers, below.
Recruiting studies
- NCT06120803RecruitingPhase 2
Esomeprazole for preventing radiation-induced esophagitis
This study tests whether a common heartburn medicine (esomeprazole) can help prevent or reduce painful swallowing caused by radiation for lung cancer. If you have stage 3 non-small cell lung cancer and are getting chemo and chest radiation, you may be able to join.
Chicago, IllinoisAges 18 years+ - NCT03866668RecruitingPhase 2
Esomeprazole for young children with autism
This Phase 2 study tests whether esomeprazole helps children with autism. It looks at children who are generally healthy, take stable medicines, and can reliably attend visits so their care team can track changes during the study.
Stanford, CaliforniaAges 2–6 - NCT06953986Recruiting
Comparing three medicines for severe acid reflux healing
This trial tests vonaprazan (two doses) against esomeprazole to see which better heals moderate-to-severe reflux esophagitis (a damaged esophagus from acid reflux) in 8 weeks. You may qualify if you have had heartburn or regurgitation for at least a month and your doctor found grade B, C, or D damage on an endoscopy.
Hyderabad, TelanganaAges 18–75 - NCT06955520Recruiting
Comparing two heartburn drugs after POEM surgery
This study compares two medications—vonoprazan and esomeprazole—to see which one heals acid reflux-related damage in the esophagus better after POEM surgery for achalasia. If you have had POEM and now have heartburn and moderate to severe esophagitis, this trial may help find the best treatment for you.
Hyderabad, TelanganaAges 18–75 - NCT02373280Recruiting
7-day tailored treatment to clear H. pylori infection
This trial tests whether a personalized 7-day treatment plan can fully get rid of H. pylori, a common stomach germ. It may help prevent ongoing stomach irritation and ulcers caused by the infection.
Seongnam-si, Gyeonggi-doAges 18–85 - NCT07537634RecruitingPhase 4
New stomach acid medicine versus standard treatment for H. pylori infection
This trial compares two different antibiotic combinations to treat H. pylori, a common stomach bacteria that causes indigestion and ulcers. One uses a newer acid-blocking medicine (vonoprazan) and the other uses a standard one (esomeprazole), both paired with antibiotics.
DhakaAges 18 years+ - NCT06509139Enrolling by invitationPhase 4
Finding the best treatment length for H. pylori infection
This study tests how long (10 or 14 days) a combination of four medicines (bismuth quadruple therapy) should be taken to best treat H. pylori infection, and whether the best duration differs between women and men. It aims to find the shortest effective treatment to reduce side effects.
TainanAges 18–100 - NCT06382493Recruiting
Tegoprazan sequential therapy for H. pylori infection
This study tests a new treatment plan using a medicine called tegoprazan for people with H. pylori, a bacteria that can cause stomach ulcers. The goal is to see if this sequential treatment works better at clearing the infection.
Seongnam-si, Gyeonggi-doAges 18 years+ - NCT04527055Enrolling by invitationPhase 4
Bismuth treatment for H. pylori: 10 or 14 days
This trial compares two common stomach medicine plans that use bismuth for 10 days versus 14 days to clear an H. pylori infection. It may help you find a shorter or more effective treatment schedule if you have H. pylori confirmed by an endoscopy.
TainanAges 18–100 - NCT06959368RecruitingPhase 4
New H. pylori treatment vs standard triple therapy
This trial compares a newer drug (vonoprazan) plus antibiotics to the standard triple therapy for eradicating H. pylori infection in the stomach. It may be a good option if you have stomach symptoms like indigestion, acid reflux, or a non-bleeding ulcer and have not been treated for H. pylori before.
Hyderabad, TelanganaAges 18–80 - NCT05874570RecruitingPhase 4
Doxycycline for H. pylori after prior treatment failure
This trial tests whether doxycycline can “rescue” or improve treatment for an H. pylori infection that has already not responded to previous therapy. It may help people whose stomach infection keeps coming back or never cleared.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT04448028RecruitingPhase 4
Stopping acid pills in liver cirrhosis: test placebo effect
This study tests whether stopping proton-pump inhibitor (PPI) acid-reducing medication is safe and works as expected for people with liver cirrhosis. Participants switch to either the study medication or a placebo (inactive pill) under close monitoring.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT05320796RecruitingPhase 4
Esomeprazole study after gastric bypass and pouch acid levels
This trial tests how well esomeprazole (a acid-reducing medicine) works after a Roux-en-Y gastric bypass, and how it changes the acidity in the stomach pouch. It may help confirm the best way to control stomach acid after bypass surgery.
Schlieren, SchlierenAges 18 years+ - NCT05582174RecruitingPhase 4
IV medicine versus pills to stop bleeding stomach ulcers
This trial compares an IV “acid-suppressing” medicine (PPI infusion) with acid pills (oral PPIs) after doctors treat a bleeding peptic ulcer endoscopically. It may help prevent re-bleeding by keeping stomach acid low while the ulcer heals.
Guangzhou, GuangdongAges 18 years+ - NCT06283381RecruitingPhase 4
Effect of heartburn drugs on stomach sleeve results
This study looks at whether taking a common heartburn medicine (proton pump inhibitor) affects the long-term results of a weight-loss procedure called Endoscopic Sleeve Gastroplasty (ESG). It might help you if you are planning to have ESG or have already had it and want to understand how acid-reducing drugs could impact your recovery and weight loss.
RomaAges 18–65 - NCT06733675RecruitingPhase 1
Safety study of a new antibiotic combination
This trial tests a new antibiotic called ceftibuten-ledaborbactam in healthy volunteers to see if it is safe and how the body processes it. You may join if you are a healthy adult and do not have allergies to certain antibiotics.
Lenexa, KansasAges 18–55 - NCT06561542RecruitingPhase 1
Safety study of LX22001 injection in healthy adults
This study tests a new injection called LX22001 in healthy volunteers to see how it is processed in the body and if it is safe. It is a first-in-human trial, so you must be in good health and meet specific age, weight, and lifestyle requirements.
Beijing, Beijing MunicipalityAges 18–45 - NCT06850480RecruitingPhase 3
Study of JP-1366 tablets for heartburn and acid reflux
This trial tests a new medication, JP-1366, for people with reflux esophagitis (damage to the esophagus from stomach acid). It aims to see if the drug is safe and effective at healing the esophagus and relieving symptoms like heartburn and regurgitation.
Beijing, Beijing MunicipalityAges 18–75 - NCT07139366RecruitingPhase 4
Probiotic plus bismuth combo for stubborn H. pylori
This study tests a combination of a probiotic (Saccharomyces boulardii) plus a standard bismuth-based four-drug treatment for people whose H. pylori infection has not been cured by previous treatments. It aims to see if adding the probiotic helps the treatment work better and cause fewer side effects.
Xi'an, ShaanxiAges 18–75 - NCT07268820RecruitingPhase 4
Nighttime heartburn treatment for erosive GERD
This trial tests a treatment for nighttime heartburn caused by GERD, a condition where stomach acid damages the esophagus. It is for adults who have had nighttime heartburn for more than 3 months and have been diagnosed with erosive GERD.
AnsanAges 19 years+
What Esomeprazole is being studied for
Conditions with recruiting Esomeprazole studies.
Common questions
- Are there clinical trials studying Esomeprazole?
- Yes. Clin2 currently lists 20 recruiting studies that include Esomeprazole, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Esomeprazole trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Esomeprazole an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Esomeprazole or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.