Testing a repurposed drug for weight loss in advanced cancer
Treatments studied
This study tests whether a drug already approved for other cancers can help patients with advanced lung, pancreatic, or colorectal cancer who are losing weight. The drug may help improve appetite and weight stability.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced (locally advanced or metastatic) lung, pancreatic, or colorectal cancer
- You are currently receiving platinum-based chemotherapy
- You have lost more than 5% of your body weight in the last 6 months, or more than 2% if your body mass index is below 20
- You are 18 years or older and have an ECOG performance status of 0, 1, or 2 (meaning you are up and about)
- Your blood test shows a GDF-15 level of at least 1500 pg/mL
- You are not pregnant or planning to become pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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