5-FU added to tear duct surgery for small tear sacs
Part of Ear, nose & throat, Eyes & vision clinical trials.
This study tests if adding a medicine called 5-FU to standard tear duct surgery helps people with a small tear drainage sac get better results. It might be an option if you have a blocked tear duct and a very small sac.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have been diagnosed with a blocked tear duct and a small tear sac (less than 3 mm wide).
- You have not had any prior tear duct or nose surgery.
- You have no known allergies to the drug 5-FU, contrast dye, or similar substances.
- You do not have serious health problems like diabetes, cancer, severe sinusitis, or certain immune conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether using four balloon inflation points during tear duct surgery works better than the standard two points for people with blocked tear ducts. It aims to improve tear drainage and reduce symptoms.
This study compares two treatments used during a surgery to unblock the tear duct. The goal is to see which one helps keep the duct open longer and reduces the chance of the blockage returning.
This trial tests a new type of dissolvable stent that slowly releases medicine to treat chronic tear duct infections that have come back after previous surgery. It may help people who need another treatment option.
This study tests a surgery called dacryocystorhinostomy (DCR) that creates a new tear drainage path to stop watery eyes. The surgery is done without a stent (a small tube), and the goal is to relieve symptoms of blocked tear ducts.
This study compares two ways to treat a blocked tear duct in babies: gentle massage of the tear sac area versus a quick probing procedure. It aims to find which method works better to clear the blockage and reduce watery eyes.
This study tests if using artificial tears (eye drops that keep your eyes moist) can prevent tear duct blockage in people receiving high-dose radioactive iodine for thyroid cancer. If you qualify, you will use artificial tears during your treatment to see if they help keep your tear ducts open.
Hear when a new Primary Acquired Nasolacrimal Duct Obstruction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.