5-FU added to tear duct surgery for small tear sacs
Part of Ear, nose & throat, Eyes & vision clinical trials.
This study tests if adding a medicine called 5-FU to standard tear duct surgery helps people with a small tear drainage sac get better results. It might be an option if you have a blocked tear duct and a very small sac.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have been diagnosed with a blocked tear duct and a small tear sac (less than 3 mm wide).
- You have not had any prior tear duct or nose surgery.
- You have no known allergies to the drug 5-FU, contrast dye, or similar substances.
- You do not have serious health problems like diabetes, cancer, severe sinusitis, or certain immune conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether using four balloon inflation points during tear duct surgery works better than the standard two points for people with blocked tear ducts. It aims to improve tear drainage and reduce symptoms.
This trial tests a new light-activated gel to help keep the tear duct open after standard surgery. It may reduce the chance of the duct closing again.
This trial compares different ways to manage the flap during external dacryocystorhinostomy (a surgery to clear blocked tear ducts). It may help if you have a blocked tear duct, a tear sac infection or a tear sac cyst or fistula.
This study compares two medications (hyaluronic acid and mitomycin-C) used during a surgery to open a blocked tear duct. It aims to see which one helps the new tear channel stay open longer, especially for people with chronic eye discharge or tearing.
This trial tests a new type of dissolvable stent that slowly releases medicine to treat chronic tear duct infections that have come back after previous surgery. It may help people who need another treatment option.
This study compares two treatments for blocked tear ducts in babies: a special eyelid massage versus a gentle probe opening (probing) with a local anesthetic cream. It helps find out which approach works better and is less stressful.
Hear when a new Primary Acquired Nasolacrimal Duct Obstruction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.