Clin2
NCT07167160Possibly a fitRecruiting

Chemo-immune therapy for stage IIICp cervical cancer

Cervical CancerImmunochemotherapy

Part of Cancer, Women’s health & pregnancy clinical trials.

This trial tests a combination of chemotherapy and immunotherapy for patients with cervical cancer that has spread to pelvic lymph nodes (stage IIICp) after radical surgery. It aims to improve outcomes by boosting the immune system's ability to fight remaining cancer cells.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
59 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You have cervical cancer that spread to pelvic lymph nodes (stage IIIC1p or IIIC2p) and have had radical surgery to remove the tumor.
  • Your cancer cells tested positive for PD-L1, a protein that can help immunotherapy work.
  • You are in generally good health, able to perform daily activities with little to no help (ECOG score 0 or 1).
  • You have not had any prior treatment with immune checkpoint inhibitors (a type of immunotherapy).
  • You do not have active autoimmune disease that requires treatment, and no cancer remaining after surgery that can be seen on scans.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06289062Recruiting· Phase 2
Chemo plus camrelizumab before surgery for stage IB1 cervical cancer

This trial tests whether giving chemotherapy combined with camrelizumab (a drug that helps the immune system fight cancer) before surgery can help women with early-stage cervical cancer who want to preserve their fertility. It is for patients whose tumors show a protein called PD-L1.

Guangzhou, Guangdong
NCT06289751Recruiting· Phase 2
Chemo-immunotherapy before surgery for stage IB2 cervical cancer

This trial tests if giving chemotherapy plus an immunotherapy drug before surgery can help shrink tumors and improve outcomes for patients with stage IB2 cervical cancer that has not been treated yet. It might be an option if you have a specific type of cervical cancer that shows a certain protein (PD-L1) on your tumor cells.

Wuhan, Hubei
NCT06288360Recruiting· Phase 2
Chemo plus immunotherapy before surgery for PD-L1-negative cervical cancer

This trial tests whether combining chemotherapy with immunotherapy before surgery can help treat cervical cancer that is PD-L1 negative. It's for women with larger tumors (stage IB3 to IIB) who have not been treated yet.

Hefei, Anhui
NCT07627620Not yet recruiting· Phase 2
Immunotherapy plus targeted therapy and chemotherapy for advanced cervical cancer

This trial tests a combination of three types of cancer-fighting drugs—an immunotherapy (camrelizumab), a targeted therapy (famitinib), and chemotherapy—to treat cervical cancer that has returned or spread. The goal is to see if this combination works better than standard treatment.

NCT05511623Recruiting· Phase 2
Tislelizumab with chemoradiotherapy for stage IIIC2 cervical cancer

This trial tests whether adding tislelizumab to standard chemotherapy and radiation works better as first treatment for stage IIIC2 cervical cancer. It aims to improve how well the cancer responds and controls the disease.

Nanning, Guangxi
NCT06288373Recruiting· Phase 2/Phase 3
Comparing chemoimmunotherapy vs chemoradiation for advanced cervical cancer before surgery

This trial tests whether a combination of chemotherapy and immunotherapy (pembrolizumab) before surgery works better than standard chemoradiation for locally advanced cervical cancer. It may help shrink tumors more effectively.

Hefei, Anhui

Hear when a new Cervical Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.