Clin2
NCT07167693Possibly a fitRecruiting

Testing arginine for diabetic ketoacidosis in type 2 diabetes

Diabetes (DM)Diabetic KetoacidosisKetosis Prone DiabetesHyperglycaemia (Diabetic)

Part of Hormones & metabolism, Immune system & allergy clinical trials.

This trial tests if an IV medicine called arginine hydrochloride can help manage diabetic ketoacidosis (DKA) in people with type 2 diabetes. It's for those who come to the ER with very high blood sugar and ketones.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
60 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You arrive at the emergency room with very high blood sugar (over 250 mg/dL) and high ketones in your blood.
  • You have a form of type 2 diabetes that can lead to DKA, and you've never been told you have type 1 diabetes.
  • You can give consent and follow the study procedures in the ER.
  • You are not on dialysis for kidney disease, do not have advanced liver disease, are not pregnant, are not allergic to arginine, and are not moderately intoxicated with alcohol.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06955416Recruiting· Phase 2/Phase 3
REAMBERIN for rehydration in diabetic ketoacidosis

This trial tests a solution called REAMBERIN to help rehydrate people with diabetic ketoacidosis (DKA). If you are 18–75 and have DKA with very high blood sugar and acidic blood, you may be able to join.

Arkhangelsk
NCT07325201Not yet recruiting· Phase 2
Preventing dangerous blood acid buildup when using SGLT2 inhibitors for type 1 diabetes

This study tests whether using a dual continuous glucose and ketone monitor can help people with type 1 diabetes safely take a class of drugs called SGLT2 inhibitors, which may improve blood sugar control but can increase the risk of diabetic ketoacidosis (DKA). By closely monitoring changes in glucose and ketone levels, the study aims to prevent dangerous episodes while benefiting from the drug's effects.

Minneapolis, Minnesota
NCT06748365Recruiting
Ferritin levels and recovery in diabetic ketoacidosis

This study looks at whether the level of a protein called ferritin in your blood can help predict how well you recover from diabetic ketoacidosis (DKA). If you have DKA and are over 18, you may be able to join.

Sohag, Sohag Governorate
NCT05855330Recruiting· Phase 2
Arginine treatment for kids hospitalized with COVID-19

This Phase 2 trial tests whether replacing the body’s arginine (an amino acid) can improve outcomes for children and young adults hospitalized with COVID-19. It may help the immune response, but you must meet several safety criteria to join.

Atlanta, Georgia
NCT06686069Not yet recruiting
Daily L-arginine supplement for blood sugar and metabolism

This trial tests whether taking an amino acid supplement called L-arginine every day can improve how the body controls blood sugar and uses insulin. It may help people with prediabetes or metabolic syndrome lower their risk of developing type 2 diabetes.

NCT07421518Not yet recruiting· Phase 2
Ketone monitoring to prevent dangerous acid buildup in type 1 diabetes

This study tests different ways to monitor ketones (substances that can build up dangerously when your body lacks insulin) to lower the risk of diabetic ketoacidosis (DKA) in people with type 1 diabetes who also take SGLT-2 inhibitors (a type of diabetes drug). You'll wear a small sensor and follow a meal plan with carbs.

Orlando, Florida

Hear when a new Diabetes (DM) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.