Gene therapy trial for early ALS patients
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This trial tests a new gene therapy called SNUG01 for adults with ALS. It aims to see if the treatment is safe and can slow the disease. You may be eligible if you are diagnosed early (within 2 years) and have good breathing function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 80 years old and have been diagnosed with ALS (definite or probable by standard criteria).
- Your first symptoms started less than 2 years ago.
- Your breathing test (FVC) is at least 70% of normal, and your ALS functional score (ALSFRS-R) is 30 or higher.
- You have a body mass index (BMI) of 19 or higher.
- You have not had gene therapy, stem cell therapy, or an organ transplant before.
- You do not have an active infection, autoimmune disease, or certain antibodies against the virus used in the treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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