ZIPPER stent-graft trial for aortic arch dissection
Part of Heart & circulation clinical trials.
This trial tests a new stent-graft device for people with a tear in the aorta (aortic arch dissection) that happened at least 2 weeks ago. It aims to see if the device can safely repair the damaged area without open surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have a tear in the upper part of the aorta (aortic arch) that is subacute (2 weeks to 3 months) or chronic (over 3 months) and needs treatment.
- The landing zone for the device in your ascending aorta must be at least 40 mm long, and the diameter must be between 24 and 47 mm.
- The openings to the main arteries in your neck and arms (innominate, left common carotid, left subclavian) must be between 6 and 24 mm wide and at least 20 mm long.
- You are considered high risk for traditional open heart surgery by two independent surgeons.
- You do not have certain other serious medical conditions like active infection, recent heart attack or stroke, severe kidney or liver problems, or connective tissue disorders like Marfan syndrome.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
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