Clin2
NCT07170995Possibly a fitRecruiting

Study of SHR-8068 with adebrelimab and chemo for lung cancer

Advanced or Metastatic Non-small Cell Lung Cancer

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a new combination of drugs (SHR-8068 plus adebrelimab and chemotherapy) against another approved combination for people with advanced non-small cell lung cancer who have not had treatment yet. The goal is to see which combination works better.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
460 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have been newly diagnosed with advanced or spreading non-small cell lung cancer and have not had any treatment for it yet.
  • Your lung cancer cannot be removed by surgery or cured with radiation and chemo together.
  • You have a tumor sample that can be tested for PD-L1 (a protein that helps decide if immunotherapy could work).
  • You are able to take care of yourself (ECOG score 0 or 1) and expected to live at least 3 months.
  • You have at least one tumor that can be measured on a scan.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06512051Recruiting· Phase 1/Phase 2
Study of SHR-A2102 and Adebrelimab for advanced lung cancer

This trial tests a combination of two drugs, SHR-A2102 and Adebrelimab, with or without other treatments, for people with advanced or metastatic non-small cell lung cancer that cannot be removed by surgery or cured with radiation. It aims to see if this approach can shrink tumors or slow the cancer's growth.

Beijing, Beijing Municipality
NCT06335355Not yet recruiting· Phase 2/Phase 3
Study of Adebrelimab plus SHR-8068 and chemo for advanced lung cancer

This trial tests a combination of two immunotherapy drugs (adebrelimab and SHR-8068) plus chemotherapy for people with advanced or spreading non-small cell lung cancer that has certain genetic changes (STK11, KEAP1, or KRAS mutations). It aims to see if this combination can shrink tumors and help people live longer.

Jinan, Shandong
NCT05416775Recruiting· Phase 1/Phase 2
Test drug SHR-8068 for advanced lung cancer

This trial tests SHR-8068 in people with advanced non-small cell lung cancer (NSCLC). It may help by controlling cancer after standard treatments have not worked, and it’s designed to find the right way to give the drug.

Hefei, Anhui
NCT06589778Recruiting· Phase 1/Phase 2
Study of three drugs for advanced lung cancer

This trial tests a combination of three drugs (SHR-A2102, Adebrelimab, and SHR-8068) for people with advanced non-small cell lung cancer that cannot be removed by surgery. It aims to see if this combination can shrink or slow the growth of the cancer.

Shanghai, Shanghai Municipality
NCT06480136Not yet recruiting· Phase 2
Study of SHR-A1921 plus adebrelimab for advanced lung cancer

This trial tests a combination of two drugs (SHR-A1921 and adebrelimab) for people with advanced non-small cell lung cancer whose cancer has grown after standard first-line treatment. The goal is to see if this new combination can help shrink tumors or slow their growth.

NCT06844474Recruiting· Phase 2
Study of SHR-1826 for advanced lung cancer

This trial tests an investigational drug called SHR-1826 for people with non-small cell lung cancer that has spread or cannot be removed by surgery. It aims to see if the drug can shrink tumors and improve outcomes.

Beijing, Beijing Municipality

Hear when a new Advanced or Metastatic Non-small Cell Lung Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.