Clin2
NCT06335355Possibly a fitNot yet recruiting

New drug combination for advanced lung cancer

Non-squamous Non-small Cell Lung Cancer

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a new combination of drugs (an immunotherapy and a possible new treatment) plus chemotherapy for people with advanced lung cancer. The goal is to see if this combination can shrink tumors or stop them from growing.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
401 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must be between 18 and 75 years old.
  • You must have been diagnosed with advanced or metastatic non-small cell lung cancer (a common type of lung cancer).
  • Your tumor must have certain genetic changes (in genes called STK11, KEAP1, or KRAS).
  • You must not have untreated or active brain metastases (tumors that have spread to the brain).
  • You must be healthy enough and have adequate organ function.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07383116Not yet recruiting· Phase 3
New combination for advanced non-squamous lung cancer

This trial tests a new drug combination for people with advanced non-squamous non-small cell lung cancer who have not had treatment before. It compares the new drug with a standard immunotherapy, both given with chemotherapy, to see which is more effective.

Shanghai
NCT05841472Recruiting· Phase 2
Camrelizumab plus chemo for advanced lung cancer without EGFR or ALK

This Phase 2 trial tests whether the immunotherapy drug camrelizumab, combined with pemetrexed and carboplatin, can work better as first treatment for advanced lung cancer that has no EGFR or ALK gene changes. You may be able to join if you have measurable disease, good enough organ function, and meet other safety rules for immune treatment.

Anam
NCT06868836Recruiting· Phase 2
Study of a new antibody combination for advanced lung cancer after targeted therapy

This trial tests a new drug (JS207) that targets both PD-1 and VEGF pathways, given alone or with other treatments, for people with advanced non-small cell lung cancer that has a specific gene change and has stopped responding to targeted therapy (TKI). The goal is to see if this combination can help shrink tumors or slow cancer growth.

Guangzhou, Guangdong
NCT07170995Recruiting· Phase 3
Study of SHR-8068 with adebrelimab and chemo for lung cancer

This trial tests a new combination of drugs (SHR-8068 plus adebrelimab and chemotherapy) against another approved combination for people with advanced non-small cell lung cancer who have not had treatment yet. The goal is to see which combination works better.

Jinan, Shandong
NCT06480136Not yet recruiting· Phase 2
Experimental drug combo for advanced lung cancer after standard treatment fails

This trial tests two new drugs—SHR-A1921 and adebrelimab—for people with advanced non-small cell lung cancer (NSCLC) whose cancer has grown after standard first-line treatment. The goal is to see if this combination can help shrink tumors or slow cancer growth.

NCT07863167Not yet recruiting· Phase 2
Combination therapy before surgery for early lung cancer

This trial tests a new drug combined with other treatments for people with lung cancer that can be removed by surgery. It aims to see if the treatment shrinks tumors before surgery and improves outcomes.

Guangzhou, Guangdong

Hear when a new Non-squamous Non-small Cell Lung Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.