Psilocybin microdosing plus therapy for hard-to-treat depression
Treatments studied
Part of Mental health clinical trials.
This trial tests whether taking very small, repeated doses of psilocybin (a substance found in magic mushrooms) along with talk therapy can help people with depression that hasn't gotten better with other treatments. You'll need to stop your current depression medications and avoid drugs or alcohol for the study period.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with major depression that hasn't improved with other treatments.
- You are willing to stop taking psychiatric medications 2 weeks before the study starts and for the whole study.
- You agree to avoid alcohol, cannabis, and all recreational drugs during the study.
- You can commit to all study visits and follow-ups, and provide a contact for someone close to you in case of an emergency.
- You are not pregnant or breastfeeding, and if you could become pregnant, you agree to use birth control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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