Psilocybin and rTMS for hard-to-treat depression
Treatments studied
Part of Mental health clinical trials.
This study tests whether a combination of psilocybin (a psychedelic substance) and transcranial magnetic stimulation (rTMS, a noninvasive brain stimulation) can help people with treatment-resistant depression. It involves daily visits to the research center for about 2 weeks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 22 and 65 years old.
- You have a current major depressive episode that has lasted at least 3 months and has not responded to at least two different antidepressant treatments.
- You are willing to stop taking antidepressants or other psychiatric medications for about 2-8 weeks before the study and stay off them for about 1 month after.
- You have not had rTMS treatment before.
- You have not used a psychedelic drug like psilocybin or LSD in the past year, and have not used them more than 5 times in your life.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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