Urine DNA test before a second bladder tumor surgery
Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial studies if a urine test for tumor DNA can help decide when a second surgery is needed for early stage bladder cancer. It may reduce unnecessary procedures for some patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have non-muscle-invasive bladder cancer (early stage, not spread into muscle)
- Your tumor is mainly urothelial carcinoma (a common type of bladder cancer)
- Your first surgery was incomplete, or the muscle layer was missing from the sample, or your tumor was stage T1
- You can give a 50 ml urine sample 2 to 6 weeks after your first surgery
- You are willing to give tumor tissue for testing and have genetic testing done
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing whether a urine test for tumor DNA/RNA can help guide the decision for a second surgery in people with high-risk, non-muscle-invasive bladder cancer. It aims to see if the urine test can predict who needs the second surgery, potentially avoiding unnecessary procedures.
This study examines whether a simple blood test can detect cancer DNA (circulating tumor DNA, or ctDNA) in patients with a specific type of bladder cancer. Detecting this DNA in blood may help doctors predict how the cancer will behave and guide future treatment decisions.
This study tests a simple urine test that looks for DNA changes to help find bladder or urinary tract cancer early. It is for people who have blood in their urine and are going to have surgery, to see if the test can accurately detect cancer before surgery.
This trial tests a new immunotherapy approach for people with a very high risk type of bladder cancer that hasn't spread into the muscle layer. The treatment is guided by a special urine test that looks for tumor DNA, and it may help if surgery cannot remove all the cancer or you choose not to have your bladder removed.
This study looks for specific DNA changes in bladder cancer tumors using a precise test. It aims to better understand the disease and may help guide future treatment choices.
This study is testing a new, non-invasive urine test that looks for specific DNA changes (methylation patterns) to find bladder cancer early. If you have bladder cancer or are a healthy person willing to help, you may be able to join.
Hear when a new Bladder Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.