Rocbrutinib for relapsed or refractory non-GCB DLBCL
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests a new targeted therapy, Rocbrutinib, for a specific type of aggressive B-cell lymphoma (non-GCB DLBCL) that has not responded to or returned after two or more prior treatments. It aims to see if Rocbrutinib can help people who have few other options.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have a specific type of DLBCL called non-GCB (confirmed by a test called Han's algorithm).
- Your lymphoma must have returned or not responded after at least two previous treatments, including one with an anti-CD20 antibody drug like Rituximab.
- You must have at least one tumor that can be measured (a lymph node larger than 1.5 cm or another organ tumor larger than 1.0 cm).
- You are not planning to have a stem cell transplant using your own cells (autologous transplant).
- You must be in reasonably good health (ECOG score of 0, 1, or 2).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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