Electrical pulse treatment for colorectal cancer that spread to the liver
Part of Cancer, Digestive system clinical trials.
This trial tests a procedure called irreversible electroporation (IRE), which uses electrical pulses to destroy liver tumors that have spread from colorectal cancer. It aims to treat liver tumors that are too small or in tricky spots for surgery, and you may also have surgery to remove some tumors if needed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older and have a confirmed diagnosis of colorectal cancer.
- You may have up to 4 liver tumors, each no larger than 4 cm (if your liver is otherwise healthy). If you've had prior liver surgery, the limit is 2 tumors.
- You must have already had at least one round of chemotherapy (with or without a targeted drug). The type is up to your doctor.
- You cannot have had any previous liver tumor ablation (destroying tumors with heat or cold).
- Your blood tests must show your liver and kidneys are working well (bilirubin under 30 µmol/L, creatinine under 150 µmol/L).
- You must be generally well enough (a performance score of 2 or less and a frailty score of 3 or less).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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