Clin2
NCT06609434Possibly a fitNot yet recruiting

Radiofrequency ablation for returning liver tumors from colorectal cancer

Colo-rectal CancerLiver Metastasis

Part of Cancer, Digestive system clinical trials.

This trial is testing whether a procedure called radiofrequency ablation (using heat to destroy tumors) is safe and effective for people whose colorectal cancer has spread to the liver and come back there. It might help if you have a few small liver tumors that cannot be removed with surgery.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
111 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have colorectal cancer that has spread to the liver, with at least 2 liver tumors that can be seen on an ultrasound.
  • The largest liver tumor must be smaller than 5 cm (about 2 inches).
  • Your liver tumors are not suitable for surgery, or you have chosen not to have surgery.
  • Any cancer outside the liver is either absent or stable.
  • You are at least 18 years old and in generally stable health.
  • You are willing to attend follow-up visits at the study center.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04062721Not yet recruiting· Phase 1
Immune system support after radiofrequency for liver tumors

This trial tests a treatment to boost the immune system after a procedure called radiofrequency ablation (RFA) that uses heat to destroy liver tumors. It is for people with colorectal cancer that has spread to the liver but not elsewhere, and aims to see if this can improve outcomes.

Boulogne-Billancourt
NCT05492136Recruiting
Radiofrequency during liver surgery to reduce cancer coming back

This study looks at whether using radiofrequency (a heat-based treatment used during surgery) during liver surgery can lower the chances that cancer returns locally. It includes people with colorectal cancer that has spread to the liver and people with liver cancer (HCC).

Barcelona
NCT06185556Recruiting· Phase 2/Phase 3
New treatments for liver tumors near blood vessels or bile ducts

This trial tests two procedures—irreversible electroporation and stereotactic body radiotherapy—for people whose colorectal cancer has spread to the liver (1–3 tumors near major blood vessels or bile ducts) and can't be surgically removed or treated with heat. The goal is to see if these approaches can safely destroy those hard-to-reach tumors.

Amsterdam, North Holland
NCT05265169Recruiting
Tested microwave ablation to treat liver metastases from colon cancer

This study tests whether a specific heating treatment (microwave ablation) can completely destroy small colon cancer spots in the liver. It may help patients who have limited liver tumors and need a precise, minimally invasive option.

Miami, Florida
NCT06590259Recruiting· Phase 2
Ablation plus drug therapy for colorectal cancer liver metastases

This trial tests a combination treatment that uses heat or cold (ablation) to destroy liver tumors along with medicines that boost your immune system to fight cancer. It is for people whose colorectal cancer has spread to the liver and who could not have surgery, or whose first treatment stopped working.

Shanghai
NCT04798898Recruiting
RFA plus immune stimulation during liver surgery for colon cancer spread

This trial looks at whether using a heat-based treatment (RFA) to trigger the immune system before or during liver surgery can improve outcomes for people with colon cancer that has spread to the liver. It’s aimed at people who plan to have the liver tumors removed because they look treatable.

Aarhus

Hear when a new Colo-rectal Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.