Endoscopic surgery for rectal cancer after chemoradiation
Part of Cancer, Digestive system clinical trials.
This trial tests whether a minimally invasive endoscopic procedure (ESD) can remove any remaining cancer in the rectum after chemoradiation, instead of more invasive surgery. It is for patients whose tumors have shrunk significantly and who want to avoid or delay major surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have rectal adenocarcinoma (a type of rectal cancer).
- You must have completed a full course of chemoradiation (chemotherapy plus radiation) to shrink the tumor.
- After treatment, your cancer must have shrunk to either a small surface growth that can be removed with endoscopy, or be nearly gone so doctors will just watch it closely.
- You cannot have cancer that has spread to other parts of the body.
- The remaining tumor must not wrap around the whole rectum or be too deep for endoscopic removal.
- You must be healthy enough for endoscopy and able to come for follow-up visits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is studying different treatments for patients with early-stage rectal cancer that has a higher chance of coming back after local removal. It looks at whether adding radiation or chemoradiation after local surgery can improve outcomes.
This study compares two approaches after early-stage rectal cancer is removed: either careful monitoring or a follow-up treatment with chemotherapy and radiation. The goal is to see which strategy works better to keep the cancer from returning.
This trial tests whether people with early- to intermediate-stage low rectal cancer can avoid surgery if their tumor responds well to a full course of chemotherapy and radiation. It starts with brief chemotherapy, then adjusts treatment based on how much the tumor shrinks.
This trial looks at whether removing the rectal tumor locally (through the anus) can work as well as a more extensive operation after scans show no remaining cancer. It may help some people avoid bigger surgery if the cancer truly appears gone after treatment.
This trial tests if adding radiation therapy after endoscopic surgery (ESD) helps people with early-stage esophageal cancer that had certain high-risk features, like deeper invasion or positive margins. It aims to improve outcomes for those who didn't get a complete cure with surgery alone.
This trial tests a new robotic system to remove large, flat growths in the rectum without traditional surgery. It may help people who have early-stage rectal tumors that are too big for standard removal methods.
Hear when a new Rectal Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.