Robot-assisted vs. manual knee replacement for severe arthritis
Part of Bones, joints & muscles clinical trials.
This study compares a robot-assisted knee replacement (MAKO) to a standard manual knee replacement. It is for people with end-stage knee arthritis who have not found relief from non-surgical treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 50 and 80 years old.
- You have severe knee arthritis (grade 4 on a common scale) that hasn't improved with treatments like physical therapy or medication.
- Your knee arthritis is not from a past injury or another disease like rheumatoid arthritis.
- You have not had any knee surgery before, except for a simple look inside (diagnostic scope) or removal of a torn piece of cartilage (meniscectomy).
- You do not have poorly controlled diabetes, active cancer, or need certain immune-suppressing medications.
- Your knee bends and straightens enough (between 15 and 100 degrees) and is not severely bowed or knock-kneed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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