Clin2
NCT07201259Possibly a fitNot yet recruiting

Gut microbiome and fertility in women receiving cancer immunotherapy

Malignant Tumors

Part of Cancer clinical trials.

This study looks at how immune checkpoint inhibitor (ICI) therapy—a type of cancer treatment that boosts your immune system—affects ovarian function and fertility in female cancer patients. It also explores the role of gut bacteria in these effects. The study aims to understand changes that may help guide fertility preservation decisions.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
40 people
Ages
18 years to 38 years
Study type
Observational

Who can take part

  • You are a woman between 18 and 38 years old.
  • You have a confirmed diagnosis of a solid tumor or soft tissue sarcoma (cancer).
  • You are scheduled to receive immune checkpoint inhibitor (ICI) therapy, either alone or with other treatments.
  • You have regular menstrual periods and are premenopausal, with normal ovarian function.
  • You haven't taken hormone medications, antibiotics, or probiotics in the required timeframes before starting.
  • You are willing to provide blood and stool samples for research.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07665697Not yet recruiting
Immunotherapy outcomes for cancer patients

This study looks at how well immunotherapy (a type of cancer treatment that helps your immune system attack cancer cells) works for people with various types of cancer. You may join if you are already planning to receive this treatment, and the study will track your outcomes to help improve future care.

Chengdu
NCT04957511Recruiting
Testing gut bacteria in gynecologic cancer patients on immunotherapy

This study looks at how gut bacteria may relate to how well immunotherapy works in people with advanced or returning gynecologic cancer. You may be asked to give stool samples several times so researchers can measure changes in your gut microbiome.

Orlando, Florida
NCT07815873Not yet recruiting
Gut microbiome study for lung, melanoma, and gynecologic cancers

This study looks at how the bacteria in your gut might affect how well immunotherapy works for certain cancers. It is for people with advanced lung cancer, melanoma, or certain gynecologic cancers who are about to start immunotherapy, and it may help doctors understand why some people respond better than others.

Milan, MI
NCT07527819Not yet recruiting
Checking ovary health after immunotherapy for triple-negative breast cancer

This study looks at how immunotherapy combined with chemotherapy affects ovary function in younger women with early-stage triple-negative breast cancer. It aims to understand if this treatment impacts fertility, which can help patients make informed decisions.

Camperdown, New South Wales
NCT07138222Recruiting
Immune therapy and fertility in women and men with melanoma

This study looks at how immune checkpoint inhibitors (a type of immunotherapy) affect fertility and hormone health in premenopausal women and men with melanoma. It aims to understand and manage these side effects while you receive treatment.

Sydney, New South Wales
NCT06945601Not yet recruiting
Pregnancy history and immunotherapy for gynecologic cancers

This study looks at how previous pregnancies affect the response to immunotherapy in women with endometrial or cervical cancer. It aims to see if pregnancy history influences treatment outcomes.

Hear when a new Malignant Tumors trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.