Clin2
NCT07202078Possibly a fitRecruiting

Starting immunoglobulin for infection prevention in hematology

MyelomaNon Hodgkin's LymphomaLeukemia

Treatments studied

Part of Blood & lymphatic, Cancer, Immune system & allergy, Infections clinical trials.

This trial tests whether giving immunoglobulin to adults with low antibody levels can prevent infections. It aims to compare immunoglobulin with antibiotic therapy or no added treatment for people with blood conditions.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
900 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are an adult with a blood condition and low antibody levels.
  • You have not had or are not scheduled for a stem cell transplant from a donor.
  • You are not already taking daily antibiotics to prevent bacterial infections.
  • You have not received immunoglobulin in the last 3 months.
  • You do not have an allergy to immunoglobulin or a known IgA deficiency with anti-IgA antibodies.
  • You are not pregnant, breastfeeding, or have severe kidney problems.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07202065Recruiting· Phase 2/Phase 3
Preventing infections with antibiotics or immunoglobulin in blood disorders

This study looks at whether a different dose of IVIg (antibody treatment through the vein) or adding antibiotics can help prevent infections in people with low antibody levels. It's for patients already on steady IVIg who cannot safely stop it.

Adelaide, South Australia
NCT07202091Recruiting· Phase 2/Phase 3
Stopping or extending immunoglobulin therapy to prevent infections

This trial tests whether it is safe to stop or extend immunoglobulin (Ig) therapy for people with low antibody levels, or if switching to preventive antibiotics works just as well to prevent infections.

Adelaide, South Australia
NCT07202052Recruiting· Phase 2/Phase 3
Antibiotics or immunoglobulin for infections in blood cancer

This trial compares two treatments—antibiotics or immunoglobulin (a blood product with infection-fighting antibodies)—to see which better prevents infections in people with certain blood cancers like CLL, multiple myeloma, or non-Hodgkin's lymphoma.

Adelaide, South Australia
NCT05678621Recruiting· Phase 2/Phase 3
Testing stopping or extending immune treatment to prevent infections

This trial studies whether people with certain blood cancers can safely stop their immune support medicine (immunoglobulin, also called Ig) or whether they should continue. It also tests antibiotic prevention strategies to reduce the risk of serious infections.

Garran, Australian Capital Territory
NCT06954441Recruiting· Phase 3
A new immune therapy for people with low IgG

This trial tests a new immunoglobulin treatment (V-Immune) for people with primary IgG deficiency who are already on IVIG therapy. It aims to see if this new therapy can effectively replace their current treatment.

Recife, Pernanbuco
NCT07017036Not yet recruiting· Phase 3
Intravenous immunoglobulin for immune deficiency

This study tests an intravenous immunoglobulin (IVIG) treatment, which is a way of giving you antibodies to help fight infections. It aims to see if this treatment is safe and effective for people with certain immune deficiencies.

Nagpur, Maharashtra

Hear when a new Myeloma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.