Clin2
NCT07203079Likely a fitNot yet recruiting

Acetaminophen: Pill vs. IV for spine surgery

Postoperative Pain

Treatments studied

Part of Pain clinical trials.

This trial compares taking acetaminophen (Tylenol) as a pill versus through an IV to manage pain after lower back fusion surgery. The goal is to see which method works better and is more convenient.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
180 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are scheduled for open lumbar laminectomy and fusion surgery on 1 to 3 vertebrae.
  • You can swallow pills.
  • You do not have any medical reason to avoid acetaminophen (Tylenol).
  • Your surgery is planned in advance, not an emergency.
  • You are not pregnant.
  • You do not have chronic pain from a cause other than your back surgery.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06484192Enrolling by invitation· Phase 4
Pain control after lower back fusion surgery

This trial tests a new pain management plan for people having spinal fusion surgery on their lower back. It aims to find the best way to control pain while reducing side effects.

Philadelphia, Pennsylvania
NCT07743606Enrolling by invitation· Phase 3
Pain medicine after lower back fusion surgery

This study tests whether taking a nonsteroidal anti-inflammatory drug (NSAID) like ibuprofen after lumbar spine fusion surgery is safe and helps with pain without affecting bone healing. It may offer an alternative to stronger pain medicines.

Philadelphia, Pennsylvania
NCT07777627Recruiting
Comparing two spinal pain relievers after lumbar spine surgery

This trial compares two different medications (morphine and dexmedetomidine) given through a spinal injection to see which provides better pain relief after lumbar spine surgery. If you qualify, you will receive one of these treatments or a placebo to help manage your pain after the operation.

Tanta, El-Gharbia
NCT07353996Recruiting· Phase 4
Finding the right dose of a new IV painkiller after bone surgery

This trial tests a single dose of a new pain medicine called tegileridine fumarate given through a vein right after orthopedic surgery (like spine, hip, or knee surgery). The goal is to find the best dose that works well for pain without causing side effects.

Hanzhong, Zhejiang
NCT07720791Not yet recruiting· Phase 4
Acetaminophen vs placebo for pain after abdominal surgery

This trial tests whether acetaminophen (a common pain reliever) works better than a placebo (a sugar pill) for pain after abdominal surgery. If you join, you will receive either the study drug or a placebo to help understand the best way to manage pain.

NCT06923540Not yet recruiting· Phase 4
IV Tylenol to reduce opioid use after surgery

This study tests whether giving acetaminophen (Tylenol) through an IV (into a vein) after abdominal surgery can help reduce the need for stronger opioid painkillers. It is for patients who cannot take pills or liquids by mouth right after surgery.

Montreal, Quebec

Hear when a new Postoperative Pain trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.