Comparing two radiation methods for primary liver cancer
Part of Cancer, Digestive system clinical trials.
This study compares two types of radiation therapy — a machine called Gamma Knife and a common technique called VMAT — to see which one works better for primary liver cancer. It aims to find out if one method is more precise in targeting the tumor while protecting healthy liver tissue, which could mean fewer side effects and better outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have primary liver cancer (cancer that starts in the liver) that cannot be removed with surgery, or you choose not to have surgery.
- Your tumor is 5 cm or smaller, and you have no more than 5 tumors.
- You are generally well enough to do most daily activities (ECOG score 0-1).
- Your liver function is fairly good (Child-Pugh grade A or B).
- You do not have serious liver-related complications like severe fluid build-up in the belly or bleeding from veins in the food pipe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two nonsurgical procedures for liver cancer: stereotactic radiosurgery (focused radiation) and radiofrequency ablation (heat therapy). It is for people whose tumor is in a tricky spot near major blood vessels or other structures, making surgery difficult, and who have not received prior treatment.
This trial tests two different ways to treat liver cancer that can't be removed with surgery. It compares stereotactic body radiation therapy (targeted high-dose radiation) with selective internal radiation therapy (tiny radioactive beads delivered through a blood vessel), both combined with immunotherapy (medicines that help your immune system fight cancer).
This study compares two ways of delivering targeted radiation to treat hepatocellular carcinoma (liver cancer): radioembolization, which uses tiny beads to deliver radiation directly through blood vessels, and external beam radiation therapy, which aims radiation from outside the body. The trial will help doctors understand which approach works better for patients with a limited number of tumors.
This trial tests whether proton beam therapy can control cancer that has spread to the liver. It may help shrink liver tumors or slow their growth while aiming to reduce harm to nearby organs.
This study compares two treatment approaches for early-stage liver cancer: standard treatments (like ablation or chemotherapy injected into blood vessels) versus a newer radiation therapy called SABR. The goal is to see which approach works better and is safer for patients with a single small tumor.
This trial tests combining radiation therapy (radioembolization) with surgery to remove part of the liver for people with a single large liver tumor (over 8 cm) that hasn't spread. The goal is to see if this approach can treat the tumor effectively.
Hear when a new Primary Liver Cancers trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.