Creatine and HMB supplements for Down syndrome
Part of Brain & nervous system, Genetic & congenital clinical trials.
This trial tests whether taking creatine and HMB supplements can improve muscle strength, reduce inflammation, and increase muscle mass in people with Down syndrome. It may help if you or your loved one can do basic physical tests like standing from a chair and do not have kidney disease or severe mobility issues.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a medical diagnosis of Down syndrome (trisomy 21).
- You need to be able to do basic physical tasks like standing from a chair or walking without help.
- You and your legal guardian must sign a consent form.
- You must not have chronic kidney disease.
- You must not have severe mobility problems that stop you from doing the tests.
- You cannot have a known allergy to creatine or inulin (the placebo).
- You cannot have taken part in another supplement study in the last 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a supplement that boosts a natural substance called NAD (which helps cells work properly) can slow or stop memory loss in people with Down syndrome. You and your caregiver would visit a clinic for regular checkups and take the supplement daily.
This trial tests if suspension therapy (a type of physical therapy using supportive straps or harnesses) can help children with Down syndrome improve their ability to move and keep their balance. It may be a helpful option for children who can already stand and walk but want to get stronger and more stable.
This trial tests if an investigational drug called donanemab can lower amyloid plaques in the brain to slow Alzheimer's disease in adults with Down syndrome. Participants must be 35–50, have elevated brain amyloid, and not have dementia yet.
This study tests whether high intensity interval training (short bursts of intense exercise) can help children with Down syndrome. Doctors want to see if it improves strength and overall health.
This study looks at the nutritional health of children with Down syndrome ages 2 to 5. It aims to find out if these kids have any special nutrition needs and how to better support their growth.
This study tests whether a medicine called memantine (already used for memory problems) can help people with Down syndrome think and remember better. Researchers will try different doses to find what works best and is safest.
Hear when a new Supplementation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.